LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | TWS119 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 5977 | 5578 | 1.0715 | 1.1315 |
| SK-BR-3 | Vemurafenib | 1.11 | uM | LJP5 | 72 | hr | 2543 | 5932 | 5578 | 1.0634 | 1.1165 |
| SK-BR-3 | Withaferin A | 1.11 | uM | LJP5 | 72 | hr | 2543 | 1858 | 5578 | 0.3332 | -0.2256 |
| SK-BR-3 | Withaferin A | 1.11 | uM | LJP6 | 72 | hr | 2543 | 1935 | 5578 | 0.3469 | -0.2005 |
| SK-BR-3 | WYE-125132 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 2052 | 5578 | 0.3678 | -0.1619 |
| SK-BR-3 | WZ3105 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 1190 | 5578 | 0.2134 | -0.4457 |
| SK-BR-3 | XMD11-50 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 3587 | 5578 | 0.6431 | 0.3440 |
| SK-BR-3 | Y39983 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 4049 | 5578 | 0.7258 | 0.4960 |
| SK-BR-3 | YM 201636 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 5427 | 5578 | 0.9728 | 0.9500 |
| SK-BR-3 | ZSTK474 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 2252 | 5578 | 0.4037 | -0.0959 |
| SK-BR-3 | Afatinib | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1938 | 5578 | 0.3474 | -0.1995 |
| SK-BR-3 | Sigma A6730 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 4423 | 5578 | 0.7930 | 0.6195 |
| SK-BR-3 | Alvocidib | 3.33 | uM | LJP6 | 72 | hr | 2543 | 902 | 5578 | 0.1618 | -0.5407 |
| SK-BR-3 | AT-7519 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 913 | 5578 | 0.1637 | -0.5371 |
| SK-BR-3 | AZD 5438 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1311 | 5578 | 0.2350 | -0.4061 |
| SK-BR-3 | AZD-6482 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 3544 | 5578 | 0.6354 | 0.3299 |
| SK-BR-3 | AZD7762 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1307 | 5578 | 0.2343 | -0.4074 |
| SK-BR-3 | AZD8055 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1791 | 5578 | 0.3212 | -0.2477 |
| SK-BR-3 | AZD8330 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 4947 | 5578 | 0.8869 | 0.7921 |
| SK-BR-3 | Barasertib | 3.33 | uM | LJP5 | 72 | hr | 2543 | 2030 | 5578 | 0.3640 | -0.1691 |
| SK-BR-3 | BI-2536 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1481 | 5578 | 0.2655 | -0.3499 |
| SK-BR-3 | BMS345541 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 2736 | 5578 | 0.4904 | 0.0634 |
| SK-BR-3 | SNS-032 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1077 | 5578 | 0.1931 | -0.4832 |
| SK-BR-3 | GDC-0980 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 1998 | 5578 | 0.3582 | -0.1796 |
| SK-BR-3 | NVP-AEW541 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 5675 | 5578 | 1.0173 | 1.0317 |