LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | A443654 | 3.33 | uM | LJP6 | 72 | hr | 1694 | 848 | 11155 | 0.0761 | -0.0894 |
| MCF7 | A443654 | 3.33 | uM | LJP6 | 72 | hr | 1389 | 803 | 5667 | 0.1418 | -0.1368 |
| MCF 10A | A443654 | 0.12 | uM | LJP6 | 72 | hr | 1694 | 7992 | 11155 | 0.7165 | 0.6657 |
| MCF 10A | A443654 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 2348 | 11155 | 0.2105 | 0.0692 |
| MCF7 | A443654 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 1052 | 5667 | 0.1857 | -0.0786 |
| MCF7 | A443654 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 804 | 5667 | 0.1419 | -0.1367 |
| Hs 578T | A443654 | 10.0 | uM | LJP6 | 72 | hr | 765 | 269 | 3124 | 0.0862 | -0.2101 |
| MCF 10A | A443654 | 0.04 | uM | LJP6 | 72 | hr | 1694 | 10311 | 11155 | 0.9243 | 0.9108 |
| MCF 10A | A443654 | 0.37 | uM | LJP6 | 72 | hr | 1694 | 3893 | 11155 | 0.3490 | 0.2324 |
| BT-20 | A443654 | 10.0 | uM | LJP6 | 72 | hr | 1334 | 232 | 3970 | 0.0586 | -0.4180 |
| MCF 10A | A443654 | 10.0 | uM | LJP6 | 72 | hr | 1694 | 538 | 11155 | 0.0483 | -0.1222 |
| MCF7 | A443654 | 0.04 | uM | LJP6 | 72 | hr | 1389 | 1385 | 5667 | 0.2445 | -0.0008 |
| MCF7 | A443654 | 0.37 | uM | LJP6 | 72 | hr | 1389 | 886 | 5667 | 0.1563 | -0.1176 |
| Hs 578T | A443654 | 0.04 | uM | LJP6 | 72 | hr | 765 | 1997 | 3124 | 0.6394 | 0.5224 |
| Hs 578T | A443654 | 0.37 | uM | LJP6 | 72 | hr | 765 | 694 | 3124 | 0.2221 | -0.0301 |
| Hs 578T | A443654 | 1.11 | uM | LJP6 | 72 | hr | 765 | 397 | 3124 | 0.1271 | -0.1560 |
| BT-20 | A443654 | 0.37 | uM | LJP6 | 72 | hr | 1334 | 2004 | 3970 | 0.5048 | 0.2540 |
| Hs 578T | A443654 | 0.12 | uM | LJP6 | 72 | hr | 765 | 1319 | 3124 | 0.4224 | 0.2351 |
| BT-20 | A443654 | 3.33 | uM | LJP6 | 72 | hr | 1334 | 809 | 3970 | 0.2039 | -0.1992 |
| BT-20 | A443654 | 0.04 | uM | LJP6 | 72 | hr | 1334 | 3139 | 3970 | 0.7907 | 0.6847 |
| BT-20 | A443654 | 0.12 | uM | LJP6 | 72 | hr | 1334 | 2994 | 3970 | 0.7540 | 0.6294 |
| BT-20 | A443654 | 1.11 | uM | LJP6 | 72 | hr | 1334 | 1361 | 3970 | 0.3428 | 0.0101 |
| Hs 578T | A443654 | 3.33 | uM | LJP6 | 72 | hr | 765 | 321 | 3124 | 0.1028 | -0.1881 |
| MDA-MB-231 | A443654 | 0.04 | uM | LJP6 | 72 | hr | 1311 | 3906 | 5013 | 0.7791 | 0.7008 |
| MCF7 | A443654 | 10.0 | uM | LJP6 | 72 | hr | 1389 | 547 | 5667 | 0.0966 | -0.1966 |