LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Mitoxantrone | 10.0 | uM | LJP6 | 72 | hr | 2543 | 295 | 5578 | 0.0529 | -0.7408 |
| SK-BR-3 | Mitoxantrone | 10.0 | uM | LJP5 | 72 | hr | 2543 | 494 | 5578 | 0.0887 | -0.6750 |
| SK-BR-3 | AT-7519 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 697 | 5578 | 0.1251 | -0.6081 |
| SK-BR-3 | Omipalisib | 10.0 | uM | LJP6 | 72 | hr | 2543 | 702 | 5578 | 0.1260 | -0.6065 |
| SK-BR-3 | AZD 5438 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 733 | 5578 | 0.1315 | -0.5963 |
| SK-BR-3 | CGP60474 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 739 | 5578 | 0.1325 | -0.5945 |
| SK-BR-3 | LDN-193189 | 10.0 | uM | LJP5 | 72 | hr | 2543 | 768 | 5578 | 0.1378 | -0.5847 |
| SK-BR-3 | Geldanamycin | 10.0 | uM | LJP5 | 72 | hr | 2543 | 837 | 5578 | 0.1502 | -0.5620 |
| SK-BR-3 | Alvocidib | 10.0 | uM | LJP6 | 72 | hr | 2543 | 878 | 5578 | 0.1575 | -0.5485 |
| SK-BR-3 | Alvocidib | 3.33 | uM | LJP6 | 72 | hr | 2543 | 902 | 5578 | 0.1618 | -0.5407 |
| SK-BR-3 | Alvocidib | 0.37 | uM | LJP6 | 72 | hr | 2543 | 905 | 5578 | 0.1623 | -0.5397 |
| SK-BR-3 | Alvocidib | 1.11 | uM | LJP6 | 72 | hr | 2543 | 911 | 5578 | 0.1633 | -0.5378 |
| SK-BR-3 | AT-7519 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 913 | 5578 | 0.1637 | -0.5371 |
| SK-BR-3 | BMS345541 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 933 | 5578 | 0.1673 | -0.5305 |
| SK-BR-3 | GSK1059615 | 10.0 | uM | LJP5 | 72 | hr | 2543 | 937 | 5578 | 0.1680 | -0.5293 |
| SK-BR-3 | SNS-032 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 993 | 5578 | 0.1780 | -0.5108 |
| SK-BR-3 | GSK1059615 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 1016 | 5578 | 0.1822 | -0.5031 |
| SK-BR-3 | A443654 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 1031 | 5578 | 0.1849 | -0.4982 |
| SK-BR-3 | Omipalisib | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1036 | 5578 | 0.1857 | -0.4967 |
| SK-BR-3 | Mitoxantrone | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1043 | 5578 | 0.1870 | -0.4944 |
| SK-BR-3 | CGP60474 | 10.0 | uM | LJP5 | 72 | hr | 2543 | 1045 | 5578 | 0.1874 | -0.4936 |
| SK-BR-3 | CGP60474 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1058 | 5578 | 0.1897 | -0.4894 |
| SK-BR-3 | SNS-032 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1077 | 5578 | 0.1931 | -0.4832 |
| SK-BR-3 | PF562271 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 1079 | 5578 | 0.1934 | -0.4825 |
| SK-BR-3 | WZ-4-145 | 10.0 | uM | LJP6 | 72 | hr | 2543 | 1089 | 5578 | 0.1952 | -0.4792 |