LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Canertinib | 10.0 | uM | LJP6 | 72 | hr | 1694 | 115 | 11155 | 0.0104 | -0.1668 |
| MCF 10A | Withaferin A | 10.0 | uM | LJP6 | 72 | hr | 1694 | 241 | 11155 | 0.0216 | -0.1536 |
| MCF 10A | AT-7519 | 10.0 | uM | LJP6 | 72 | hr | 1694 | 253 | 11155 | 0.0227 | -0.1523 |
| MCF 10A | CGP60474 | 3.33 | uM | LJP6 | 72 | hr | 1694 | 279 | 11155 | 0.0251 | -0.1495 |
| MCF 10A | Alvocidib | 3.33 | uM | LJP6 | 72 | hr | 1694 | 289 | 11155 | 0.0260 | -0.1485 |
| MCF 10A | LDN-193189 | 10.0 | uM | LJP5 | 72 | hr | 1694 | 294 | 11155 | 0.0264 | -0.1480 |
| MCF 10A | Withaferin A | 10.0 | uM | LJP5 | 72 | hr | 1694 | 297 | 11155 | 0.0267 | -0.1476 |
| MCF 10A | Alvocidib | 1.11 | uM | LJP6 | 72 | hr | 1694 | 299 | 11155 | 0.0269 | -0.1474 |
| MCF 10A | Alvocidib | 0.37 | uM | LJP6 | 72 | hr | 1694 | 300 | 11155 | 0.0269 | -0.1474 |
| MCF 10A | CGP60474 | 0.12 | uM | LJP6 | 72 | hr | 1694 | 306 | 11155 | 0.0275 | -0.1467 |
| MCF 10A | SNS-032 | 3.33 | uM | LJP6 | 72 | hr | 1694 | 308 | 11155 | 0.0276 | -0.1465 |
| MCF 10A | SNS-032 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 309 | 11155 | 0.0278 | -0.1463 |
| MCF 10A | AT-7519 | 3.33 | uM | LJP6 | 72 | hr | 1694 | 314 | 11155 | 0.0282 | -0.1459 |
| MCF 10A | Alvocidib | 10.0 | uM | LJP6 | 72 | hr | 1694 | 336 | 11155 | 0.0301 | -0.1436 |
| MCF 10A | CGP60474 | 0.37 | uM | LJP6 | 72 | hr | 1694 | 364 | 11155 | 0.0326 | -0.1406 |
| MCF 10A | CGP60474 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 364 | 11155 | 0.0327 | -0.1406 |
| MCF 10A | SNS-032 | 10.0 | uM | LJP6 | 72 | hr | 1694 | 366 | 11155 | 0.0328 | -0.1404 |
| MCF 10A | WZ3105 | 10.0 | uM | LJP5 | 72 | hr | 1694 | 371 | 11155 | 0.0333 | -0.1398 |
| MCF 10A | WZ3105 | 3.33 | uM | LJP5 | 72 | hr | 1694 | 386 | 11155 | 0.0346 | -0.1382 |
| MCF 10A | CGP60474 | 0.04 | uM | LJP6 | 72 | hr | 1694 | 387 | 11155 | 0.0347 | -0.1382 |
| MCF 10A | Celastrol | 3.33 | uM | LJP6 | 72 | hr | 1694 | 403 | 11155 | 0.0361 | -0.1365 |
| MCF 10A | CGP60474 | 0.37 | uM | LJP5 | 72 | hr | 1694 | 405 | 11155 | 0.0363 | -0.1363 |
| MCF 10A | Withaferin A | 3.33 | uM | LJP6 | 72 | hr | 1694 | 405 | 11155 | 0.0363 | -0.1362 |
| MCF 10A | CGP60474 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 408 | 11155 | 0.0366 | -0.1360 |
| MCF 10A | WZ3105 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 426 | 11155 | 0.0382 | -0.1340 |