LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 LDN-193189
0.04
uM
LJP5
 72
hr
 1334 4142 3970 1.0431 1.0649
BT-20 Nilotinib
3.33
uM
LJP5
 72
hr
 1334 4174 3970 1.0511 1.0770
BT-20 Dactolisib
3.33
uM
LJP5
 72
hr
 1334 1375 3970 0.3464 0.0154
BT-20 WH-4-025
0.37
uM
LJP5
 72
hr
 1334 2805 3970 0.7065 0.5579
BT-20 SB590885
0.04
uM
LJP5
 72
hr
 1334 4237 3970 1.0671 1.1011
BT-20 XMD16-144
0.37
uM
LJP5
 72
hr
 1334 1362 3970 0.3431 0.0105
BT-20 Brivanib
0.37
uM
LJP5
 72
hr
 1334 3929 3970 0.9895 0.9842
BT-20 Buparlisib
0.37
uM
LJP5
 72
hr
 1334 2698 3970 0.6795 0.5173
BT-20 BX-912
0.37
uM
LJP5
 72
hr
 1334 3753 3970 0.9451 0.9173
BT-20 NVP-AEW541
0.12
uM
LJP5
 72
hr
 1334 4059 3970 1.0222 1.0334
BT-20 SB590885
0.12
uM
LJP5
 72
hr
 1334 4065 3970 1.0239 1.0359
BT-20 CGP60474
0.37
uM
LJP5
 72
hr
 1334 410 3970 0.1033 -0.3508
BT-20 PIK-93
0.12
uM
LJP5
 72
hr
 1334 4135 3970 1.0414 1.0624
BT-20 LDN-193189
0.37
uM
LJP5
 72
hr
 1334 3952 3970 0.9953 0.9930
BT-20 CP724714
0.37
uM
LJP5
 72
hr
 1334 3663 3970 0.9225 0.8832
BT-20 CP466722
0.37
uM
LJP5
 72
hr
 1334 4028 3970 1.0145 1.0219
BT-20 Crizotinib
0.37
uM
LJP5
 72
hr
 1334 3429 3970 0.8636 0.7946
BT-20 Momelotinib
0.37
uM
LJP5
 72
hr
 1334 3659 3970 0.9215 0.8817
BT-20 Dasatinib
0.37
uM
LJP5
 72
hr
 1334 1596 3970 0.4021 0.0994
BT-20 Luminespib
0.12
uM
LJP5
 72
hr
 1334 945 3970 0.2380 -0.1478
BT-20 Dovitinib
0.37
uM
LJP5
 72
hr
 1334 2549 3970 0.6421 0.4609
BT-20 Enzastaurin
0.37
uM
LJP5
 72
hr
 1334 4117 3970 1.0370 1.0557
BT-20 Erlotinib
0.37
uM
LJP5
 72
hr
 1334 3961 3970 0.9976 0.9964
BT-20 Foretinib
0.37
uM
LJP5
 72
hr
 1334 1368 3970 0.3446 0.0128
BT-20 PLX-4720
3.33
uM
LJP5
 72
hr
 1334 3389 3970 0.8536 0.7795