LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Dasatinib | 0.12 | uM | LJP6 | 72 | hr | 1389 | 1097 | 5667 | 0.1936 | -0.0682 |
| MCF7 | Dovitinib | 0.12 | uM | LJP5 | 72 | hr | 1389 | 5308 | 5667 | 0.9365 | 0.9159 |
| MCF7 | Enzastaurin | 0.12 | uM | LJP5 | 72 | hr | 1389 | 5864 | 5667 | 1.0346 | 1.0458 |
| MCF7 | Erlotinib | 0.12 | uM | LJP5 | 72 | hr | 1389 | 5720 | 5667 | 1.0093 | 1.0123 |
| MCF7 | Foretinib | 0.12 | uM | LJP5 | 72 | hr | 1389 | 3798 | 5667 | 0.6701 | 0.5630 |
| MCF7 | R406 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 5075 | 5667 | 0.8954 | 0.8614 |
| MCF7 | Pictilisib | 0.12 | uM | LJP6 | 72 | hr | 1389 | 2178 | 5667 | 0.3843 | 0.1845 |
| MCF7 | Gefitinib | 0.12 | uM | LJP6 | 72 | hr | 1389 | 5776 | 5667 | 1.0191 | 1.0253 |
| MCF7 | Geldanamycin | 0.12 | uM | LJP5 | 72 | hr | 1389 | 1923 | 5667 | 0.3393 | 0.1248 |
| MCF7 | Geldanamycin | 0.12 | uM | LJP6 | 72 | hr | 1389 | 1825 | 5667 | 0.3221 | 0.1020 |
| MCF7 | GSK1059615 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 5372 | 5667 | 0.9479 | 0.9310 |
| MCF7 | GSK1059615 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 4636 | 5667 | 0.8179 | 0.7588 |
| MCF7 | GSK1904529A | 0.12 | uM | LJP6 | 72 | hr | 1389 | 3406 | 5667 | 0.6009 | 0.4714 |
| MCF7 | Omipalisib | 0.12 | uM | LJP6 | 72 | hr | 1389 | 1383 | 5667 | 0.2440 | -0.0014 |
| MCF7 | GSK 690693 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 4163 | 5667 | 0.7345 | 0.6483 |
| MCF7 | GW843682X | 0.12 | uM | LJP6 | 72 | hr | 1389 | 3078 | 5667 | 0.5431 | 0.3948 |
| MCF7 | HG-5-113-01 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 4556 | 5667 | 0.8038 | 0.7401 |
| MCF7 | HG-5-88-01 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 3585 | 5667 | 0.6325 | 0.5132 |
| MCF7 | Imatinib | 0.12 | uM | LJP6 | 72 | hr | 1389 | 6237 | 5667 | 1.1005 | 1.1331 |
| MCF7 | JNK-9L | 0.12 | uM | LJP6 | 72 | hr | 1389 | 4020 | 5667 | 0.7094 | 0.6150 |
| MCF7 | JW-7-24-1 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 3595 | 5667 | 0.6344 | 0.5157 |
| MCF7 | Lapatinib | 0.12 | uM | LJP6 | 72 | hr | 1389 | 5503 | 5667 | 0.9710 | 0.9616 |
| MCF7 | LDN-193189 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 5484 | 5667 | 0.9676 | 0.9571 |
| MCF7 | Linifanib | 0.12 | uM | LJP6 | 72 | hr | 1389 | 4928 | 5667 | 0.8695 | 0.8271 |
| MCF7 | Linsitinib | 0.12 | uM | LJP5 | 72 | hr | 1389 | 5148 | 5667 | 0.9084 | 0.8786 |