LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | GSK1059615 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 2596 | 11155 | 0.2328 | 0.0954 |
| MCF 10A | GSK1059615 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 3081 | 11155 | 0.2762 | 0.1466 |
| MCF 10A | GSK1904529A | 1.11 | uM | LJP6 | 72 | hr | 1694 | 6263 | 11155 | 0.5615 | 0.4829 |
| MCF 10A | Omipalisib | 1.11 | uM | LJP6 | 72 | hr | 1694 | 1636 | 11155 | 0.1467 | -0.0062 |
| MCF 10A | GSK 690693 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 9787 | 11155 | 0.8773 | 0.8553 |
| MCF 10A | GW843682X | 1.11 | uM | LJP6 | 72 | hr | 1694 | 1859 | 11155 | 0.1666 | 0.0174 |
| MCF 10A | HG-5-113-01 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 7639 | 11155 | 0.6848 | 0.6284 |
| MCF 10A | HG-5-88-01 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 7479 | 11155 | 0.6705 | 0.6114 |
| MCF 10A | Imatinib | 1.11 | uM | LJP6 | 72 | hr | 1694 | 11255 | 11155 | 1.0089 | 1.0105 |
| MCF 10A | JNK-9L | 1.11 | uM | LJP6 | 72 | hr | 1694 | 2873 | 11155 | 0.2576 | 0.1247 |
| MCF 10A | JW-7-24-1 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 11652 | 11155 | 1.0445 | 1.0525 |
| MCF 10A | Lapatinib | 1.11 | uM | LJP6 | 72 | hr | 1694 | 9605 | 11155 | 0.8610 | 0.8361 |
| MCF 10A | LDN-193189 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 10759 | 11155 | 0.9644 | 0.9581 |
| MCF 10A | Linifanib | 1.11 | uM | LJP6 | 72 | hr | 1694 | 11428 | 11155 | 1.0245 | 1.0289 |
| MCF 10A | Linsitinib | 1.11 | uM | LJP5 | 72 | hr | 1694 | 8544 | 11155 | 0.7659 | 0.7240 |
| MCF 10A | Mitoxantrone | 1.11 | uM | LJP5 | 72 | hr | 1694 | 1422 | 11155 | 0.1275 | -0.0287 |
| MCF 10A | Mitoxantrone | 1.11 | uM | LJP6 | 72 | hr | 1694 | 1380 | 11155 | 0.1237 | -0.0332 |
| MCF 10A | MK2206 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 10727 | 11155 | 0.9616 | 0.9547 |
| MCF 10A | Neratinib | 1.11 | uM | LJP5 | 72 | hr | 1694 | 3257 | 11155 | 0.2920 | 0.1652 |
| MCF 10A | Nilotinib | 1.11 | uM | LJP5 | 72 | hr | 1694 | 11291 | 11155 | 1.0122 | 1.0143 |
| MCF 10A | Nintedanib | 1.11 | uM | LJP6 | 72 | hr | 1694 | 10827 | 11155 | 0.9706 | 0.9653 |
| MCF 10A | NU7441 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 10716 | 11155 | 0.9606 | 0.9536 |
| MCF 10A | Dactolisib | 1.11 | uM | LJP5 | 72 | hr | 1694 | 2858 | 11155 | 0.2562 | 0.1230 |
| MCF 10A | NVP-TAE684 | 1.11 | uM | LJP6 | 72 | hr | 1694 | 6073 | 11155 | 0.5444 | 0.4628 |
| MCF 10A | Palbociclib | 1.11 | uM | LJP6 | 72 | hr | 1694 | 6292 | 11155 | 0.5640 | 0.4860 |