LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|
BT-20 | WZ-4-145 | 0.04 | uM | LJP6 | 72 | hr | 1657 | 4689 | 5505 | 0.8517 | 0.7879 |
BT-20 | XMD16-144 | 0.04 | uM | LJP5 | 72 | hr | 1657 | 5393 | 5505 | 0.9797 | 0.9709 |
BT-20 | Brivanib | 0.04 | uM | LJP5 | 72 | hr | 1657 | 5266 | 5505 | 0.9565 | 0.9377 |
BT-20 | Buparlisib | 0.04 | uM | LJP5 | 72 | hr | 1657 | 5689 | 5505 | 1.0334 | 1.0477 |
BT-20 | BX-912 | 0.04 | uM | LJP5 | 72 | hr | 1657 | 5063 | 5505 | 0.9197 | 0.8851 |
BT-20 | Canertinib | 0.04 | uM | LJP6 | 72 | hr | 1657 | 4885 | 5505 | 0.8874 | 0.8389 |
BT-20 | Celastrol | 0.04 | uM | LJP6 | 72 | hr | 1657 | 5828 | 5505 | 1.0587 | 1.0839 |
BT-20 | CGP60474 | 0.04 | uM | LJP5 | 72 | hr | 1657 | 5524 | 5505 | 1.0034 | 1.0049 |
BT-20 | CGP60474 | 0.04 | uM | LJP6 | 72 | hr | 1657 | 1217 | 5505 | 0.2211 | -0.1145 |
BT-20 | CHIR-99021 | 0.04 | uM | LJP6 | 72 | hr | 1657 | 5553 | 5505 | 1.0087 | 1.0124 |
BT-20 | CP724714 | 0.04 | uM | LJP5 | 72 | hr | 1657 | 5207 | 5505 | 0.9459 | 0.9226 |
BT-20 | CP466722 | 0.04 | uM | LJP5 | 72 | hr | 1657 | 5939 | 5505 | 1.0788 | 1.1127 |
BT-20 | Crizotinib | 0.04 | uM | LJP5 | 72 | hr | 1657 | 4615 | 5505 | 0.8384 | 0.7687 |
BT-20 | Momelotinib | 0.04 | uM | LJP5 | 72 | hr | 1657 | 4869 | 5505 | 0.8844 | 0.8345 |
BT-20 | Dasatinib | 0.04 | uM | LJP5 | 72 | hr | 1657 | 5156 | 5505 | 0.9365 | 0.9091 |
BT-20 | Dasatinib | 0.04 | uM | LJP6 | 72 | hr | 1657 | 2745 | 5505 | 0.4986 | 0.2826 |
BT-20 | Dovitinib | 0.04 | uM | LJP5 | 72 | hr | 1657 | 4715 | 5505 | 0.8565 | 0.7947 |
BT-20 | Enzastaurin | 0.04 | uM | LJP5 | 72 | hr | 1657 | 6123 | 5505 | 1.1122 | 1.1605 |
BT-20 | Erlotinib | 0.04 | uM | LJP5 | 72 | hr | 1657 | 4819 | 5505 | 0.8753 | 0.8216 |
BT-20 | Foretinib | 0.04 | uM | LJP5 | 72 | hr | 1657 | 5724 | 5505 | 1.0397 | 1.0568 |
BT-20 | R406 | 0.04 | uM | LJP6 | 72 | hr | 1657 | 5812 | 5505 | 1.0556 | 1.0796 |
BT-20 | Pictilisib | 0.04 | uM | LJP6 | 72 | hr | 1657 | 4409 | 5505 | 0.8009 | 0.7151 |
BT-20 | Gefitinib | 0.04 | uM | LJP6 | 72 | hr | 1657 | 5762 | 5505 | 1.0466 | 1.0667 |
BT-20 | Geldanamycin | 0.04 | uM | LJP5 | 72 | hr | 1657 | 2646 | 5505 | 0.4806 | 0.2568 |
BT-20 | Geldanamycin | 0.04 | uM | LJP6 | 72 | hr | 1657 | 2703 | 5505 | 0.4910 | 0.2716 |