LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T CGP60474
0.37
uM
LJP5
 72
hr
 929 837 3228 0.2594 -0.0400
Hs 578T CGP60474
0.37
uM
LJP6
 72
hr
 929 849 3228 0.2631 -0.0348
Hs 578T CP724714
0.37
uM
LJP5
 72
hr
 929 3087 3228 0.9563 0.9386
Hs 578T CP466722
0.37
uM
LJP5
 72
hr
 929 3448 3228 1.0682 1.0958
Hs 578T Afatinib
0.04
uM
LJP6
 72
hr
 929 3069 3228 0.9509 0.9311
Hs 578T Sigma A6730
0.04
uM
LJP5
 72
hr
 929 3170 3228 0.9822 0.9750
Hs 578T AT-7519
0.04
uM
LJP6
 72
hr
 929 3200 3228 0.9913 0.9878
Hs 578T AZD 5438
0.04
uM
LJP6
 72
hr
 929 2947 3228 0.9129 0.8777
Hs 578T AZD8055
0.04
uM
LJP6
 72
hr
 929 1457 3228 0.4516 0.2299
Hs 578T AZD8330
0.04
uM
LJP5
 72
hr
 929 1531 3228 0.4745 0.2621
Hs 578T BI-2536
0.04
uM
LJP6
 72
hr
 929 899 3228 0.2787 -0.0129
Hs 578T BMS345541
0.04
uM
LJP6
 72
hr
 929 3254 3228 1.0082 1.0116
Hs 578T SB590885
0.04
uM
LJP5
 72
hr
 929 3913 3228 1.2123 1.2981
Hs 578T PIK-93
0.04
uM
LJP5
 72
hr
 929 3293 3228 1.0203 1.0285
Hs 578T Alpelisib
0.04
uM
LJP5
 72
hr
 929 3166 3228 0.9808 0.9730
Hs 578T Luminespib
0.04
uM
LJP5
 72
hr
 929 1342 3228 0.4157 0.1796
Hs 578T XMD11-85h
0.04
uM
LJP6
 72
hr
 929 3182 3228 0.9857 0.9800
Hs 578T HG-6-64-01
0.04
uM
LJP6
 72
hr
 929 3750 3228 1.1619 1.2273
Hs 578T WZ-4-145
0.04
uM
LJP6
 72
hr
 929 2380 3228 0.7373 0.6311
Hs 578T XMD16-144
0.04
uM
LJP5
 72
hr
 929 1812 3228 0.5614 0.3842
Hs 578T Celastrol
0.04
uM
LJP6
 72
hr
 929 3393 3228 1.0511 1.0717
Hs 578T CGP60474
0.04
uM
LJP5
 72
hr
 929 3045 3228 0.9433 0.9204
Hs 578T CHIR-99021
0.04
uM
LJP6
 72
hr
 929 3117 3228 0.9657 0.9518
Hs 578T Foretinib
0.37
uM
LJP5
 72
hr
 929 2054 3228 0.6364 0.4894
Hs 578T Erlotinib
0.37
uM
LJP5
 72
hr
 929 3071 3228 0.9515 0.9318