LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T Pelitinib
0.12
uM
LJP5
 72
hr
 929 3189 3228 0.9879 0.9830
Hs 578T PF562271
0.12
uM
LJP6
 72
hr
 929 2628 3228 0.8142 0.7391
Hs 578T PHA-665752
0.12
uM
LJP5
 72
hr
 929 3242 3228 1.0044 1.0062
Hs 578T PI103
0.12
uM
LJP6
 72
hr
 929 1583 3228 0.4906 0.2847
Hs 578T PLX-4720
0.12
uM
LJP5
 72
hr
 929 3612 3228 1.1191 1.1673
Hs 578T Radicicol
0.12
uM
LJP6
 72
hr
 929 3262 3228 1.0106 1.0149
Hs 578T Seliciclib
0.12
uM
LJP5
 72
hr
 929 3309 3228 1.0251 1.0352
Hs 578T XL147
0.12
uM
LJP5
 72
hr
 929 3292 3228 1.0199 1.0280
Hs 578T Saracatinib
0.12
uM
LJP6
 72
hr
 929 2885 3228 0.8939 0.8511
Hs 578T Sorafenib
0.12
uM
LJP6
 72
hr
 929 3812 3228 1.1810 1.2542
Hs 578T SU11274
0.12
uM
LJP5
 72
hr
 929 3198 3228 0.9907 0.9869
Hs 578T TGX221
0.12
uM
LJP5
 72
hr
 929 2824 3228 0.8750 0.8245
Hs 578T Torin1
0.12
uM
LJP6
 72
hr
 929 1391 3228 0.4310 0.2010
Hs 578T Vemurafenib
0.12
uM
LJP5
 72
hr
 929 3356 3228 1.0396 1.0557
Hs 578T Withaferin A
0.12
uM
LJP5
 72
hr
 929 3298 3228 1.0219 1.0307
Hs 578T WYE-125132
0.12
uM
LJP6
 72
hr
 929 1340 3228 0.4151 0.1787
Hs 578T WZ3105
0.12
uM
LJP5
 72
hr
 929 835 3228 0.2589 -0.0407
Hs 578T YM 201636
0.12
uM
LJP5
 72
hr
 929 3228 3228 1.0001 1.0001
Hs 578T ZSTK474
0.12
uM
LJP6
 72
hr
 929 2261 3228 0.7006 0.5796
Hs 578T Sigma A6730
0.37
uM
LJP5
 72
hr
 929 3035 3228 0.9402 0.9160
Hs 578T Alvocidib
0.37
uM
LJP6
 72
hr
 929 734 3228 0.2274 -0.0849
Hs 578T AZD7762
0.37
uM
LJP6
 72
hr
 929 1146 3228 0.3551 0.0944
Hs 578T AZD8055
0.37
uM
LJP6
 72
hr
 929 1276 3228 0.3955 0.1511
Hs 578T Luminespib
0.37
uM
LJP5
 72
hr
 929 1311 3228 0.4062 0.1662
Hs 578T Alpelisib
0.37
uM
LJP5
 72
hr
 929 2926 3228 0.9065 0.8688