LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A CGP60474
0.37
uM
LJP5
 72
hr
 513 685 10401 0.0659 0.0174
MCF 10A CGP60474
0.37
uM
LJP6
 72
hr
 513 572 10401 0.0550 0.0059
MCF 10A CP724714
0.37
uM
LJP5
 72
hr
 513 10181 10401 0.9788 0.9777
MCF 10A CP466722
0.37
uM
LJP5
 72
hr
 513 10725 10401 1.0312 1.0328
MCF 10A Afatinib
0.04
uM
LJP6
 72
hr
 513 351 10401 0.0338 -0.0164
MCF 10A Sigma A6730
0.04
uM
LJP5
 72
hr
 513 9985 10401 0.9600 0.9580
MCF 10A AT-7519
0.04
uM
LJP6
 72
hr
 513 9912 10401 0.9530 0.9505
MCF 10A AZD 5438
0.04
uM
LJP6
 72
hr
 513 9444 10401 0.9080 0.9033
MCF 10A AZD8055
0.04
uM
LJP6
 72
hr
 513 2503 10401 0.2407 0.2013
MCF 10A AZD8330
0.04
uM
LJP5
 72
hr
 513 447 10401 0.0430 -0.0067
MCF 10A BI-2536
0.04
uM
LJP6
 72
hr
 513 739 10401 0.0711 0.0228
MCF 10A BMS345541
0.04
uM
LJP6
 72
hr
 513 10692 10401 1.0280 1.0294
MCF 10A SB590885
0.04
uM
LJP5
 72
hr
 513 10835 10401 1.0417 1.0439
MCF 10A PIK-93
0.04
uM
LJP5
 72
hr
 513 10310 10401 0.9913 0.9908
MCF 10A Alpelisib
0.04
uM
LJP5
 72
hr
 513 9455 10401 0.9090 0.9043
MCF 10A Luminespib
0.04
uM
LJP5
 72
hr
 513 474 10401 0.0456 -0.0040
MCF 10A XMD11-85h
0.04
uM
LJP6
 72
hr
 513 9036 10401 0.8688 0.8620
MCF 10A HG-6-64-01
0.04
uM
LJP6
 72
hr
 513 11110 10401 1.0682 1.0717
MCF 10A WZ-4-145
0.04
uM
LJP6
 72
hr
 513 8831 10401 0.8491 0.8413
MCF 10A XMD16-144
0.04
uM
LJP5
 72
hr
 513 8960 10401 0.8615 0.8543
MCF 10A Celastrol
0.04
uM
LJP6
 72
hr
 513 11579 10401 1.1132 1.1191
MCF 10A CGP60474
0.04
uM
LJP5
 72
hr
 513 4985 10401 0.4793 0.4523
MCF 10A CHIR-99021
0.04
uM
LJP6
 72
hr
 513 9979 10401 0.9594 0.9573
MCF 10A Foretinib
0.37
uM
LJP5
 72
hr
 513 8179 10401 0.7864 0.7753
MCF 10A Erlotinib
0.37
uM
LJP5
 72
hr
 513 2357 10401 0.2266 0.1865