LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 Crizotinib
3.33
uM
LJP5
 72
hr
 1657 3569 5505 0.6483 0.4968
BT-20 Dasatinib
3.33
uM
LJP6
 72
hr
 1657 1159 5505 0.2106 -0.1294
BT-20 Dovitinib
3.33
uM
LJP5
 72
hr
 1657 2475 5505 0.4495 0.2124
BT-20 Erlotinib
3.33
uM
LJP5
 72
hr
 1657 4827 5505 0.8768 0.8237
BT-20 Foretinib
3.33
uM
LJP5
 72
hr
 1657 1624 5505 0.2950 -0.0087
BT-20 Afatinib
3.33
uM
LJP6
 72
hr
 1657 4854 5505 0.8817 0.8307
BT-20 Sigma A6730
3.33
uM
LJP5
 72
hr
 1657 5110 5505 0.9283 0.8974
BT-20 AT-7519
3.33
uM
LJP6
 72
hr
 1657 1217 5505 0.2210 -0.1145
BT-20 AZD 5438
3.33
uM
LJP6
 72
hr
 1657 1657 5505 0.3010 -0.0002
BT-20 AZD8055
3.33
uM
LJP6
 72
hr
 1657 1826 5505 0.3317 0.0438
BT-20 AZD8330
3.33
uM
LJP5
 72
hr
 1657 4563 5505 0.8288 0.7550
BT-20 BI-2536
3.33
uM
LJP6
 72
hr
 1657 1630 5505 0.2961 -0.0072
BT-20 BMS345541
3.33
uM
LJP6
 72
hr
 1657 4482 5505 0.8142 0.7341
BT-20 SB590885
3.33
uM
LJP5
 72
hr
 1657 5640 5505 1.0244 1.0349
BT-20 PIK-93
3.33
uM
LJP5
 72
hr
 1657 4260 5505 0.7739 0.6765
BT-20 Alpelisib
3.33
uM
LJP5
 72
hr
 1657 2120 5505 0.3851 0.1202
BT-20 Luminespib
3.33
uM
LJP5
 72
hr
 1657 1774 5505 0.3222 0.0302
BT-20 XMD11-85h
3.33
uM
LJP6
 72
hr
 1657 5117 5505 0.9295 0.8991
BT-20 HG-6-64-01
3.33
uM
LJP6
 72
hr
 1657 2994 5505 0.5438 0.3473
BT-20 WZ-4-145
3.33
uM
LJP6
 72
hr
 1657 4261 5505 0.7741 0.6767
BT-20 XMD16-144
3.33
uM
LJP5
 72
hr
 1657 1958 5505 0.3556 0.0780
BT-20 Celastrol
3.33
uM
LJP6
 72
hr
 1657 860 5505 0.1562 -0.2073
BT-20 CGP60474
3.33
uM
LJP5
 72
hr
 1657 1342 5505 0.2438 -0.0821
BT-20 Geldanamycin
3.33
uM
LJP6
 72
hr
 1657 1656 5505 0.3008 -0.0005
BT-20 Geldanamycin
3.33
uM
LJP5
 72
hr
 1657 1735 5505 0.3153 0.0203