LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
SK-BR-3 Trametinib
3.33
uM
LJP5
 72
hr
 1476 2661 3694 0.7205 0.5344
MCF 10A PHA-665752
10.0
uM
LJP5
 72
hr
 513 684 10401 0.0658 0.0173
SK-BR-3 Radicicol
1.11
uM
LJP5
 72
hr
 1476 1697 3694 0.4596 0.0996
MDA-MB-231 WZ3105
0.37
uM
LJP5
 72
hr
 868 735 3486 0.2108 -0.0508
MCF 10A PLX-4720
10.0
uM
LJP5
 72
hr
 513 7135 10401 0.6860 0.6697
SK-BR-3 TWS119
3.33
uM
LJP5
 72
hr
 1476 2449 3694 0.6630 0.4385
SK-BR-3 Seliciclib
1.11
uM
LJP5
 72
hr
 1476 3292 3694 0.8912 0.8187
MCF 10A Radicicol
10.0
uM
LJP5
 72
hr
 513 347 10401 0.0334 -0.0168
MDA-MB-231 YM 201636
0.37
uM
LJP5
 72
hr
 868 3142 3486 0.9014 0.8687
MCF 10A Seliciclib
10.0
uM
LJP5
 72
hr
 513 1269 10401 0.1220 0.0764
MCF 10A Ruxolitinib
10.0
uM
LJP5
 72
hr
 513 6672 10401 0.6415 0.6229
MCF 10A XL147
10.0
uM
LJP5
 72
hr
 513 4774 10401 0.4590 0.4309
SK-BR-3 Ruxolitinib
1.11
uM
LJP5
 72
hr
 1476 3603 3694 0.9754 0.9591
SK-BR-3 LDN-193189
0.12
uM
LJP5
 72
hr
 1476 4191 3694 1.1346 1.2243
MDA-MB-231 Sigma A6730
1.11
uM
LJP5
 72
hr
 868 2611 3486 0.7491 0.6659