LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Crizotinib | 0.04 | uM | LJP5 | 72 | hr | 1476 | 2870 | 3694 | 0.7771 | 0.6287 |
| SK-BR-3 | Dasatinib | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3729 | 3694 | 1.0095 | 1.0158 |
| SK-BR-3 | Dovitinib | 0.04 | uM | LJP5 | 72 | hr | 1476 | 2818 | 3694 | 0.7630 | 0.6052 |
| SK-BR-3 | Erlotinib | 0.04 | uM | LJP5 | 72 | hr | 1476 | 3031 | 3694 | 0.8206 | 0.7011 |
| SK-BR-3 | Foretinib | 0.04 | uM | LJP5 | 72 | hr | 1476 | 3955 | 3694 | 1.0706 | 1.1177 |
| SK-BR-3 | Afatinib | 0.04 | uM | LJP6 | 72 | hr | 1476 | 1371 | 3694 | 0.3713 | -0.0474 |
| SK-BR-3 | Sigma A6730 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 2787 | 3694 | 0.7545 | 0.5909 |
| SK-BR-3 | AT-7519 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3146 | 3694 | 0.8516 | 0.7528 |
| SK-BR-3 | AZD 5438 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3484 | 3694 | 0.9431 | 0.9053 |
| SK-BR-3 | AZD8055 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 1566 | 3694 | 0.4239 | 0.0403 |
| SK-BR-3 | AZD8330 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 2449 | 3694 | 0.6631 | 0.4386 |
| SK-BR-3 | BI-2536 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 1485 | 3694 | 0.4021 | 0.0039 |
| SK-BR-3 | BMS345541 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3872 | 3694 | 1.0482 | 1.0803 |
| SK-BR-3 | SB590885 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 4098 | 3694 | 1.1094 | 1.1822 |
| SK-BR-3 | PIK-93 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 4081 | 3694 | 1.1048 | 1.1747 |
| SK-BR-3 | Alpelisib | 0.04 | uM | LJP5 | 72 | hr | 1476 | 3411 | 3694 | 0.9235 | 0.8725 |
| SK-BR-3 | Luminespib | 0.04 | uM | LJP5 | 72 | hr | 1476 | 1618 | 3694 | 0.4381 | 0.0639 |
| SK-BR-3 | XMD11-85h | 0.04 | uM | LJP6 | 72 | hr | 1476 | 2628 | 3694 | 0.7115 | 0.5194 |
| SK-BR-3 | HG-6-64-01 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 4118 | 3694 | 1.1148 | 1.1912 |
| SK-BR-3 | WZ-4-145 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 2226 | 3694 | 0.6027 | 0.3381 |
| SK-BR-3 | XMD16-144 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 2078 | 3694 | 0.5626 | 0.2713 |
| SK-BR-3 | Celastrol | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3474 | 3694 | 0.9406 | 0.9011 |
| SK-BR-3 | CGP60474 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 4222 | 3694 | 1.1429 | 1.2381 |
| SK-BR-3 | Geldanamycin | 0.04 | uM | LJP6 | 72 | hr | 1476 | 1492 | 3694 | 0.4041 | 0.0072 |
| SK-BR-3 | Geldanamycin | 0.04 | uM | LJP5 | 72 | hr | 1476 | 1472 | 3694 | 0.3985 | -0.0021 |