LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 WZ-4-145
0.37
uM
LJP6
 72
hr
 1235 2493 4156 0.5998 0.4306
MCF7 XMD16-144
0.37
uM
LJP5
 72
hr
 1235 1788 4156 0.4303 0.1893
MCF7 Brivanib
0.37
uM
LJP5
 72
hr
 1235 3561 4156 0.8569 0.7963
MCF7 Buparlisib
0.37
uM
LJP5
 72
hr
 1235 1528 4156 0.3678 0.1004
MCF7 BX-912
0.37
uM
LJP5
 72
hr
 1235 3339 4156 0.8035 0.7203
MCF7 Canertinib
0.37
uM
LJP6
 72
hr
 1235 3194 4156 0.7686 0.6707
MCF7 Celastrol
0.37
uM
LJP6
 72
hr
 1235 2047 4156 0.4927 0.2781
MCF7 CGP60474
0.37
uM
LJP5
 72
hr
 1235 777 4156 0.1870 -0.1568
MCF7 CGP60474
0.37
uM
LJP6
 72
hr
 1235 592 4156 0.1426 -0.2201
MCF7 CHIR-99021
0.37
uM
LJP6
 72
hr
 1235 3231 4156 0.7774 0.6833
MCF7 CP724714
0.37
uM
LJP5
 72
hr
 1235 3410 4156 0.8205 0.7445
MCF7 CP466722
0.37
uM
LJP5
 72
hr
 1235 4829 4156 1.1619 1.2304
MCF7 Crizotinib
0.37
uM
LJP5
 72
hr
 1235 2485 4156 0.5979 0.4278
MCF7 Momelotinib
0.37
uM
LJP5
 72
hr
 1235 3297 4156 0.7934 0.7061
MCF7 Dasatinib
0.37
uM
LJP5
 72
hr
 1235 906 4156 0.2182 -0.1125
MCF7 Dasatinib
0.37
uM
LJP6
 72
hr
 1235 972 4156 0.2339 -0.0902
MCF7 Dovitinib
0.37
uM
LJP5
 72
hr
 1235 3010 4156 0.7242 0.6076
MCF7 Enzastaurin
0.37
uM
LJP5
 72
hr
 1235 4352 4156 1.0472 1.0672
MCF7 Erlotinib
0.37
uM
LJP5
 72
hr
 1235 4342 4156 1.0447 1.0636
MCF7 Foretinib
0.37
uM
LJP5
 72
hr
 1235 1523 4156 0.3665 0.0986
MCF7 R406
0.37
uM
LJP6
 72
hr
 1235 3615 4156 0.8698 0.8147
MCF7 Pictilisib
0.37
uM
LJP6
 72
hr
 1235 1203 4156 0.2895 -0.0111
MCF7 Gefitinib
0.37
uM
LJP6
 72
hr
 1235 4531 4156 1.0902 1.1283
MCF7 Geldanamycin
0.37
uM
LJP5
 72
hr
 1235 1395 4156 0.3357 0.0548
MCF7 Geldanamycin
0.37
uM
LJP6
 72
hr
 1235 1321 4156 0.3178 0.0293