LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T GW843682X
0.37
uM
LJP6
 72
hr
 929 1074 3228 0.3329 0.0633
Hs 578T HG-5-113-01
0.37
uM
LJP5
 72
hr
 929 2663 3228 0.8250 0.7542
Hs 578T HG-5-88-01
0.37
uM
LJP6
 72
hr
 929 2918 3228 0.9041 0.8653
Hs 578T Imatinib
0.37
uM
LJP6
 72
hr
 929 3333 3228 1.0325 1.0456
Hs 578T JNK-9L
0.37
uM
LJP6
 72
hr
 929 2930 3228 0.9079 0.8706
Hs 578T JW-7-24-1
0.37
uM
LJP6
 72
hr
 929 2608 3228 0.8081 0.7306
Hs 578T Lapatinib
0.37
uM
LJP6
 72
hr
 929 3087 3228 0.9563 0.9386
Hs 578T LDN-193189
0.37
uM
LJP5
 72
hr
 929 2947 3228 0.9130 0.8779
Hs 578T Linifanib
0.37
uM
LJP6
 72
hr
 929 3052 3228 0.9455 0.9234
Hs 578T Linsitinib
0.37
uM
LJP5
 72
hr
 929 2995 3228 0.9279 0.8988
Hs 578T Mitoxantrone
0.37
uM
LJP5
 72
hr
 929 935 3228 0.2897 0.0025
Hs 578T Mitoxantrone
0.37
uM
LJP6
 72
hr
 929 894 3228 0.2770 -0.0153
Hs 578T MK2206
0.37
uM
LJP6
 72
hr
 929 1743 3228 0.5400 0.3540
Hs 578T Neratinib
0.37
uM
LJP5
 72
hr
 929 2418 3228 0.7493 0.6479
Hs 578T Nilotinib
0.37
uM
LJP5
 72
hr
 929 3705 3228 1.1480 1.2078
Hs 578T Nintedanib
0.37
uM
LJP6
 72
hr
 929 2350 3228 0.7280 0.6180
Hs 578T NU7441
0.37
uM
LJP5
 72
hr
 929 2959 3228 0.9168 0.8831
Hs 578T Dactolisib
0.37
uM
LJP5
 72
hr
 929 1307 3228 0.4050 0.1645
Hs 578T NVP-TAE684
0.37
uM
LJP6
 72
hr
 929 2237 3228 0.6932 0.5692
Hs 578T Palbociclib
0.37
uM
LJP6
 72
hr
 929 1791 3228 0.5550 0.3752
Hs 578T PD0325901
0.37
uM
LJP5
 72
hr
 929 1618 3228 0.5014 0.2999
Hs 578T PD0325901
0.37
uM
LJP6
 72
hr
 929 1591 3228 0.4930 0.2880
Hs 578T PD173074
0.37
uM
LJP6
 72
hr
 929 2869 3228 0.8890 0.8441
Hs 578T PD184352
0.37
uM
LJP5
 72
hr
 929 2014 3228 0.6240 0.4720
Hs 578T Pelitinib
0.37
uM
LJP5
 72
hr
 929 2918 3228 0.9042 0.8654