LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Canertinib | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1403 | 3694 | 0.3799 | -0.0331 |
| SK-BR-3 | Celastrol | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1243 | 3694 | 0.3367 | -0.1051 |
| SK-BR-3 | CGP60474 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1172 | 3694 | 0.3174 | -0.1373 |
| SK-BR-3 | CGP60474 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 992 | 3694 | 0.2685 | -0.2186 |
| SK-BR-3 | CHIR-99021 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 2894 | 3694 | 0.7835 | 0.6393 |
| SK-BR-3 | CP724714 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1692 | 3694 | 0.4582 | 0.0974 |
| SK-BR-3 | CP466722 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3268 | 3694 | 0.8848 | 0.8080 |
| SK-BR-3 | Crizotinib | 1.11 | uM | LJP5 | 72 | hr | 1476 | 2462 | 3694 | 0.6666 | 0.4445 |
| SK-BR-3 | Momelotinib | 1.11 | uM | LJP5 | 72 | hr | 1476 | 2684 | 3694 | 0.7267 | 0.5446 |
| SK-BR-3 | Dasatinib | 1.11 | uM | LJP5 | 72 | hr | 1476 | 2992 | 3694 | 0.8101 | 0.6837 |
| SK-BR-3 | Dasatinib | 1.11 | uM | LJP6 | 72 | hr | 1476 | 3228 | 3694 | 0.8739 | 0.7900 |
| SK-BR-3 | Dovitinib | 1.11 | uM | LJP5 | 72 | hr | 1476 | 2571 | 3694 | 0.6960 | 0.4935 |
| SK-BR-3 | Enzastaurin | 1.11 | uM | LJP5 | 72 | hr | 1476 | 4019 | 3694 | 1.0881 | 1.1469 |
| SK-BR-3 | Erlotinib | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3339 | 3694 | 0.9041 | 0.8402 |
| SK-BR-3 | Foretinib | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1376 | 3694 | 0.3727 | -0.0451 |
| SK-BR-3 | R406 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 4206 | 3694 | 1.1387 | 1.2310 |
| SK-BR-3 | Pictilisib | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1808 | 3694 | 0.4895 | 0.1496 |
| SK-BR-3 | Gefitinib | 1.11 | uM | LJP6 | 72 | hr | 1476 | 2219 | 3694 | 0.6009 | 0.3351 |
| SK-BR-3 | Geldanamycin | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1545 | 3694 | 0.4183 | 0.0309 |
| SK-BR-3 | Geldanamycin | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1467 | 3694 | 0.3973 | -0.0041 |
| SK-BR-3 | GSK1059615 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1535 | 3694 | 0.4155 | 0.0263 |
| SK-BR-3 | GSK1059615 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1490 | 3694 | 0.4034 | 0.0060 |
| SK-BR-3 | GSK1904529A | 1.11 | uM | LJP6 | 72 | hr | 1476 | 3473 | 3694 | 0.9402 | 0.9003 |
| SK-BR-3 | Omipalisib | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1277 | 3694 | 0.3457 | -0.0901 |
| SK-BR-3 | GSK 690693 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 2793 | 3694 | 0.7561 | 0.5936 |