LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | PD0325901 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 3408 | 3694 | 0.9227 | 0.8713 |
| SK-BR-3 | PD0325901 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3700 | 3694 | 1.0016 | 1.0027 |
| SK-BR-3 | PD173074 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 4309 | 3694 | 1.1665 | 1.2773 |
| SK-BR-3 | PD184352 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 4125 | 3694 | 1.1168 | 1.1945 |
| SK-BR-3 | Pelitinib | 0.04 | uM | LJP5 | 72 | hr | 1476 | 3025 | 3694 | 0.8189 | 0.6983 |
| SK-BR-3 | PF431396 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 3883 | 3694 | 1.0511 | 1.0852 |
| SK-BR-3 | PF477736 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 1745 | 3694 | 0.4726 | 0.1213 |
| SK-BR-3 | PF562271 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3808 | 3694 | 1.0309 | 1.0515 |
| SK-BR-3 | PHA-665752 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 4062 | 3694 | 1.0997 | 1.1661 |
| SK-BR-3 | PHA-793887 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 1591 | 3694 | 0.4307 | 0.0515 |
| SK-BR-3 | PI103 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3483 | 3694 | 0.9430 | 0.9050 |
| SK-BR-3 | PLX-4720 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 3715 | 3694 | 1.0059 | 1.0097 |
| SK-BR-3 | QL-X-138 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 2215 | 3694 | 0.5998 | 0.3333 |
| SK-BR-3 | QL-XII-47 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 2440 | 3694 | 0.6605 | 0.4344 |
| SK-BR-3 | Radicicol | 0.04 | uM | LJP5 | 72 | hr | 1476 | 2137 | 3694 | 0.5787 | 0.2981 |
| SK-BR-3 | Radicicol | 0.04 | uM | LJP6 | 72 | hr | 1476 | 2022 | 3694 | 0.5475 | 0.2461 |
| SK-BR-3 | Seliciclib | 0.04 | uM | LJP5 | 72 | hr | 1476 | 4165 | 3694 | 1.1275 | 1.2124 |
| SK-BR-3 | Ruxolitinib | 0.04 | uM | LJP5 | 72 | hr | 1476 | 3180 | 3694 | 0.8608 | 0.7682 |
| SK-BR-3 | XL147 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 4230 | 3694 | 1.1453 | 1.2420 |
| SK-BR-3 | Saracatinib | 0.04 | uM | LJP6 | 72 | hr | 1476 | 4233 | 3694 | 1.1459 | 1.2431 |
| SK-BR-3 | Selumetinib | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3967 | 3694 | 1.0740 | 1.1232 |
| SK-BR-3 | Sirolimus | 0.04 | uM | LJP6 | 72 | hr | 1476 | 2466 | 3694 | 0.6677 | 0.4463 |
| SK-BR-3 | Sorafenib | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3306 | 3694 | 0.8951 | 0.8253 |
| SK-BR-3 | SU11274 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 4337 | 3694 | 1.1741 | 1.2901 |
| SK-BR-3 | Fedratinib | 0.04 | uM | LJP5 | 72 | hr | 1476 | 4159 | 3694 | 1.1260 | 1.2100 |