LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
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BT-20 | TGX221 | 10.0 | uM | LJP5 | 1 | H19 | 72 | hr | 1097 | 3884 | 3769 | 1.0304 | 1.0428 |
BT-20 | TGX221 | 10.0 | uM | LJP5 | 2 | H19 | 72 | hr | 1097 | 3982 | 3769 | 1.0564 | 1.0795 |
BT-20 | TGX221 | 10.0 | uM | LJP5 | 3 | H19 | 72 | hr | 1097 | 4046 | 3769 | 1.0733 | 1.1035 |
BT-20 | Torin1 | 10.0 | uM | LJP6 | 1 | O13 | 72 | hr | 1097 | 651 | 3769 | 0.1727 | -0.1670 |
BT-20 | Torin1 | 10.0 | uM | LJP6 | 2 | O13 | 72 | hr | 1097 | 657 | 3769 | 0.1743 | -0.1648 |
BT-20 | Torin1 | 10.0 | uM | LJP6 | 3 | O13 | 72 | hr | 1097 | 701 | 3769 | 0.1860 | -0.1483 |
BT-20 | Torin2 | 10.0 | uM | LJP5 | 1 | I19 | 72 | hr | 1097 | 730 | 3769 | 0.1937 | -0.1374 |
BT-20 | Torin2 | 10.0 | uM | LJP5 | 2 | I19 | 72 | hr | 1097 | 616 | 3769 | 0.1634 | -0.1801 |
BT-20 | Torin2 | 10.0 | uM | LJP5 | 3 | I19 | 72 | hr | 1097 | 622 | 3769 | 0.1650 | -0.1779 |
BT-20 | Tozasertib | 10.0 | uM | LJP5 | 1 | B13 | 72 | hr | 1097 | 1286 | 3769 | 0.3412 | 0.0706 |
BT-20 | Tozasertib | 10.0 | uM | LJP5 | 2 | B13 | 72 | hr | 1097 | 1261 | 3769 | 0.3345 | 0.0613 |
BT-20 | Tozasertib | 10.0 | uM | LJP5 | 3 | B13 | 72 | hr | 1097 | 1272 | 3769 | 0.3374 | 0.0654 |
BT-20 | Trametinib | 10.0 | uM | LJP5 | 1 | P19 | 72 | hr | 1097 | 2722 | 3769 | 0.7221 | 0.6080 |
BT-20 | Trametinib | 10.0 | uM | LJP5 | 2 | P19 | 72 | hr | 1097 | 3100 | 3769 | 0.8224 | 0.7495 |
BT-20 | Trametinib | 10.0 | uM | LJP5 | 3 | P19 | 72 | hr | 1097 | 2926 | 3769 | 0.7762 | 0.6843 |
BT-20 | TWS119 | 10.0 | uM | LJP5 | 1 | M01 | 72 | hr | 1097 | 828 | 3769 | 0.2197 | -0.1008 |
BT-20 | TWS119 | 10.0 | uM | LJP5 | 2 | M01 | 72 | hr | 1097 | 1155 | 3769 | 0.3064 | 0.0216 |
BT-20 | TWS119 | 10.0 | uM | LJP5 | 3 | M01 | 72 | hr | 1097 | 1465 | 3769 | 0.3886 | 0.1376 |
BT-20 | Vemurafenib | 10.0 | uM | LJP5 | 1 | C13 | 72 | hr | 1097 | 2455 | 3769 | 0.6513 | 0.5081 |
BT-20 | Vemurafenib | 10.0 | uM | LJP5 | 2 | C13 | 72 | hr | 1097 | 2444 | 3769 | 0.6484 | 0.5040 |
BT-20 | Vemurafenib | 10.0 | uM | LJP5 | 3 | C13 | 72 | hr | 1097 | 2393 | 3769 | 0.6348 | 0.4849 |
BT-20 | Withaferin A | 10.0 | uM | LJP5 | 1 | G13 | 72 | hr | 1097 | 652 | 3769 | 0.1730 | -0.1666 |
BT-20 | Withaferin A | 10.0 | uM | LJP5 | 2 | G13 | 72 | hr | 1097 | 603 | 3769 | 0.1600 | -0.1850 |
BT-20 | Withaferin A | 10.0 | uM | LJP5 | 3 | G13 | 72 | hr | 1097 | 590 | 3769 | 0.1565 | -0.1898 |
BT-20 | Withaferin A | 10.0 | uM | LJP6 | 1 | G13 | 72 | hr | 1097 | 578 | 3769 | 0.1533 | -0.1943 |