LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
Hs 578T Neratinib
0.04
uM
LJP5
 2
A18
 72
hr
 658 3333 3846 0.8666 0.8390
Hs 578T Neratinib
0.04
uM
LJP5
 3
A18
 72
hr
 658 3601 3846 0.9363 0.9231
Hs 578T Nilotinib
0.04
uM
LJP5
 1
N18
 72
hr
 658 4126 3846 1.0728 1.0878
Hs 578T Nilotinib
0.04
uM
LJP5
 2
N18
 72
hr
 658 3952 3846 1.0275 1.0332
Hs 578T Nilotinib
0.04
uM
LJP5
 3
N18
 72
hr
 658 4149 3846 1.0788 1.0950
Hs 578T Nintedanib
0.04
uM
LJP6
 1
H06
 72
hr
 658 3524 3846 0.9163 0.8990
Hs 578T Nintedanib
0.04
uM
LJP6
 2
H06
 72
hr
 658 3794 3846 0.9865 0.9837
Hs 578T Nintedanib
0.04
uM
LJP6
 3
H06
 72
hr
 658 3350 3846 0.8710 0.8444
Hs 578T NU7441
0.04
uM
LJP5
 1
C12
 72
hr
 658 3705 3846 0.9633 0.9557
Hs 578T NU7441
0.04
uM
LJP5
 2
C12
 72
hr
 658 3686 3846 0.9584 0.9498
Hs 578T NU7441
0.04
uM
LJP5
 3
C12
 72
hr
 658 3887 3846 1.0106 1.0128
Hs 578T Dactolisib
0.04
uM
LJP5
 1
M18
 72
hr
 658 1136 3846 0.2954 0.1499
Hs 578T Dactolisib
0.04
uM
LJP5
 2
M18
 72
hr
 658 1144 3846 0.2974 0.1524
Hs 578T Dactolisib
0.04
uM
LJP5
 3
M18
 72
hr
 658 1211 3846 0.3149 0.1734
Hs 578T NVP-TAE684
0.04
uM
LJP6
 1
K18
 72
hr
 658 2963 3846 0.7704 0.7230
Hs 578T NVP-TAE684
0.04
uM
LJP6
 2
K18
 72
hr
 658 3148 3846 0.8185 0.7810
Hs 578T NVP-TAE684
0.04
uM
LJP6
 3
K18
 72
hr
 658 3129 3846 0.8136 0.7751
Hs 578T Palbociclib
0.04
uM
LJP6
 1
E18
 72
hr
 658 2388 3846 0.6209 0.5426
Hs 578T Palbociclib
0.04
uM
LJP6
 2
E18
 72
hr
 658 2355 3846 0.6123 0.5323
Hs 578T Palbociclib
0.04
uM
LJP6
 3
E18
 72
hr
 658 2341 3846 0.6087 0.5279
Hs 578T PD0325901
0.04
uM
LJP5
 1
C06
 72
hr
 658 2304 3846 0.5991 0.5163
Hs 578T PD0325901
0.04
uM
LJP5
 2
C06
 72
hr
 658 2392 3846 0.6219 0.5439
Hs 578T PD0325901
0.04
uM
LJP5
 3
C06
 72
hr
 658 2242 3846 0.5829 0.4968
Hs 578T PD0325901
0.04
uM
LJP6
 1
E06
 72
hr
 658 2165 3846 0.5629 0.4727
Hs 578T PD0325901
0.04
uM
LJP6
 2
E06
 72
hr
 658 2287 3846 0.5946 0.5109