LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 Withaferin A
10.0
uM
LJP6
 2
G13
 72
hr
 1097 568 3769 0.1507 -0.1981
BT-20 Withaferin A
10.0
uM
LJP6
 3
G13
 72
hr
 1097 553 3769 0.1467 -0.2037
BT-20 WYE-125132
10.0
uM
LJP6
 1
L07
 72
hr
 1097 957 3769 0.2539 -0.0525
BT-20 WYE-125132
10.0
uM
LJP6
 2
L07
 72
hr
 1097 1090 3769 0.2892 -0.0027
BT-20 WYE-125132
10.0
uM
LJP6
 3
L07
 72
hr
 1097 982 3769 0.2605 -0.0431
BT-20 WZ3105
10.0
uM
LJP5
 1
D19
 72
hr
 1097 624 3769 0.1655 -0.1771
BT-20 WZ3105
10.0
uM
LJP5
 2
D19
 72
hr
 1097 636 3769 0.1687 -0.1726
BT-20 WZ3105
10.0
uM
LJP5
 3
D19
 72
hr
 1097 724 3769 0.1921 -0.1397
BT-20 XMD11-50
10.0
uM
LJP6
 1
P07
 72
hr
 1097 1182 3769 0.3136 0.0317
BT-20 XMD11-50
10.0
uM
LJP6
 2
P07
 72
hr
 1097 1246 3769 0.3305 0.0557
BT-20 XMD11-50
10.0
uM
LJP6
 3
P07
 72
hr
 1097 1394 3769 0.3698 0.1111
BT-20 Y39983
10.0
uM
LJP6
 1
P01
 72
hr
 1097 1451 3769 0.3849 0.1324
BT-20 Y39983
10.0
uM
LJP6
 2
P01
 72
hr
 1097 1515 3769 0.4019 0.1563
BT-20 Y39983
10.0
uM
LJP6
 3
P01
 72
hr
 1097 1594 3769 0.4229 0.1859
BT-20 YM 201636
10.0
uM
LJP5
 1
N07
 72
hr
 1097 1048 3769 0.2780 -0.0184
BT-20 YM 201636
10.0
uM
LJP5
 2
N07
 72
hr
 1097 1245 3769 0.3303 0.0553
BT-20 YM 201636
10.0
uM
LJP5
 3
N07
 72
hr
 1097 985 3769 0.2613 -0.0420
BT-20 ZSTK474
10.0
uM
LJP6
 1
M13
 72
hr
 1097 982 3769 0.2605 -0.0431
BT-20 ZSTK474
10.0
uM
LJP6
 2
M13
 72
hr
 1097 889 3769 0.2358 -0.0779
BT-20 ZSTK474
10.0
uM
LJP6
 3
M13
 72
hr
 1097 906 3769 0.2404 -0.0716
Hs 578T Afatinib
0.04
uM
LJP6
 1
G24
 72
hr
 658 3551 3846 0.9233 0.9074
Hs 578T Afatinib
0.04
uM
LJP6
 2
G24
 72
hr
 658 3643 3846 0.9472 0.9363
Hs 578T Afatinib
0.04
uM
LJP6
 3
G24
 72
hr
 658 3476 3846 0.9038 0.8839
Hs 578T Sigma A6730
0.04
uM
LJP5
 1
B24
 72
hr
 658 3740 3846 0.9724 0.9667
Hs 578T Sigma A6730
0.04
uM
LJP5
 2
B24
 72
hr
 658 3777 3846 0.9820 0.9783