LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
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BT-20 | CGP60474 | 10.0 | uM | LJP6 | 2 | G01 | 72 | hr | 1097 | 424 | 3769 | 0.1125 | -0.2519 |
BT-20 | CGP60474 | 10.0 | uM | LJP6 | 3 | G01 | 72 | hr | 1097 | 415 | 3769 | 0.1101 | -0.2553 |
BT-20 | CHIR-99021 | 10.0 | uM | LJP6 | 1 | P13 | 72 | hr | 1097 | 2583 | 3769 | 0.6852 | 0.5560 |
BT-20 | CHIR-99021 | 10.0 | uM | LJP6 | 2 | P13 | 72 | hr | 1097 | 2840 | 3769 | 0.7534 | 0.6522 |
BT-20 | CHIR-99021 | 10.0 | uM | LJP6 | 3 | P13 | 72 | hr | 1097 | 3011 | 3769 | 0.7988 | 0.7162 |
BT-20 | CP724714 | 10.0 | uM | LJP5 | 1 | A07 | 72 | hr | 1097 | 1780 | 3769 | 0.4722 | 0.2555 |
BT-20 | CP724714 | 10.0 | uM | LJP5 | 2 | A07 | 72 | hr | 1097 | 2409 | 3769 | 0.6391 | 0.4909 |
BT-20 | CP724714 | 10.0 | uM | LJP5 | 3 | A07 | 72 | hr | 1097 | 2512 | 3769 | 0.6664 | 0.5294 |
BT-20 | CP466722 | 10.0 | uM | LJP5 | 1 | I07 | 72 | hr | 1097 | 1807 | 3769 | 0.4794 | 0.2656 |
BT-20 | CP466722 | 10.0 | uM | LJP5 | 2 | I07 | 72 | hr | 1097 | 2113 | 3769 | 0.5606 | 0.3801 |
BT-20 | CP466722 | 10.0 | uM | LJP5 | 3 | I07 | 72 | hr | 1097 | 2119 | 3769 | 0.5621 | 0.3824 |
BT-20 | Crizotinib | 10.0 | uM | LJP5 | 1 | A19 | 72 | hr | 1097 | 1066 | 3769 | 0.2828 | -0.0117 |
BT-20 | Crizotinib | 10.0 | uM | LJP5 | 2 | A19 | 72 | hr | 1097 | 1044 | 3769 | 0.2770 | -0.0199 |
BT-20 | Crizotinib | 10.0 | uM | LJP5 | 3 | A19 | 72 | hr | 1097 | 1146 | 3769 | 0.3040 | 0.0182 |
BT-20 | Momelotinib | 10.0 | uM | LJP5 | 1 | P07 | 72 | hr | 1097 | 994 | 3769 | 0.2637 | -0.0386 |
BT-20 | Momelotinib | 10.0 | uM | LJP5 | 2 | P07 | 72 | hr | 1097 | 1055 | 3769 | 0.2799 | -0.0158 |
BT-20 | Momelotinib | 10.0 | uM | LJP5 | 3 | P07 | 72 | hr | 1097 | 1138 | 3769 | 0.3019 | 0.0152 |
BT-20 | Dasatinib | 10.0 | uM | LJP5 | 1 | D01 | 72 | hr | 1097 | 874 | 3769 | 0.2319 | -0.0835 |
BT-20 | Dasatinib | 10.0 | uM | LJP5 | 2 | D01 | 72 | hr | 1097 | 1262 | 3769 | 0.3348 | 0.0616 |
BT-20 | Dasatinib | 10.0 | uM | LJP5 | 3 | D01 | 72 | hr | 1097 | 1159 | 3769 | 0.3075 | 0.0231 |
BT-20 | Dasatinib | 10.0 | uM | LJP6 | 1 | I01 | 72 | hr | 1097 | 840 | 3769 | 0.2228 | -0.0963 |
BT-20 | Dasatinib | 10.0 | uM | LJP6 | 2 | I01 | 72 | hr | 1097 | 787 | 3769 | 0.2088 | -0.1161 |
BT-20 | Dasatinib | 10.0 | uM | LJP6 | 3 | I01 | 72 | hr | 1097 | 744 | 3769 | 0.1974 | -0.1322 |
BT-20 | Dovitinib | 10.0 | uM | LJP5 | 1 | E19 | 72 | hr | 1097 | 1396 | 3769 | 0.3703 | 0.1118 |
BT-20 | Dovitinib | 10.0 | uM | LJP5 | 2 | E19 | 72 | hr | 1097 | 1324 | 3769 | 0.3512 | 0.0849 |