LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 Mitoxantrone
3.33
uM
LJP5
 1
C20
 72
hr
 1097 665 3769 0.1764 -0.1618
BT-20 Mitoxantrone
3.33
uM
LJP5
 2
C20
 72
hr
 1097 777 3769 0.2061 -0.1198
BT-20 Mitoxantrone
3.33
uM
LJP5
 3
C20
 72
hr
 1097 632 3769 0.1677 -0.1741
BT-20 Mitoxantrone
3.33
uM
LJP6
 1
C20
 72
hr
 1097 753 3769 0.1998 -0.1288
BT-20 Mitoxantrone
3.33
uM
LJP6
 2
C20
 72
hr
 1097 621 3769 0.1647 -0.1782
BT-20 Mitoxantrone
3.33
uM
LJP6
 3
C20
 72
hr
 1097 599 3769 0.1589 -0.1865
BT-20 MK2206
3.33
uM
LJP6
 1
F02
 72
hr
 1097 1810 3769 0.4802 0.2667
BT-20 MK2206
3.33
uM
LJP6
 2
F02
 72
hr
 1097 1712 3769 0.4542 0.2300
BT-20 MK2206
3.33
uM
LJP6
 3
F02
 72
hr
 1097 1599 3769 0.4242 0.1878
BT-20 Neratinib
3.33
uM
LJP5
 1
A14
 72
hr
 1097 1496 3769 0.3969 0.1492
BT-20 Neratinib
3.33
uM
LJP5
 2
A14
 72
hr
 1097 1632 3769 0.4329 0.2001
BT-20 Neratinib
3.33
uM
LJP5
 3
A14
 72
hr
 1097 2016 3769 0.5348 0.3438
BT-20 Nilotinib
3.33
uM
LJP5
 1
N14
 72
hr
 1097 3622 3769 0.9609 0.9448
BT-20 Nilotinib
3.33
uM
LJP5
 2
N14
 72
hr
 1097 3770 3769 1.0001 1.0002
BT-20 Nilotinib
3.33
uM
LJP5
 3
N14
 72
hr
 1097 3811 3769 1.0110 1.0155
BT-20 Nintedanib
3.33
uM
LJP6
 1
H02
 72
hr
 1097 2686 3769 0.7126 0.5945
BT-20 Nintedanib
3.33
uM
LJP6
 2
H02
 72
hr
 1097 2750 3769 0.7295 0.6185
BT-20 Nintedanib
3.33
uM
LJP6
 3
H02
 72
hr
 1097 2440 3769 0.6473 0.5025
BT-20 NU7441
3.33
uM
LJP5
 1
C08
 72
hr
 1097 3115 3769 0.8264 0.7551
BT-20 NU7441
3.33
uM
LJP5
 2
C08
 72
hr
 1097 2809 3769 0.7452 0.6406
BT-20 NU7441
3.33
uM
LJP5
 3
C08
 72
hr
 1097 3220 3769 0.8542 0.7944
BT-20 Dactolisib
3.33
uM
LJP5
 1
M14
 72
hr
 1097 1376 3769 0.3650 0.1043
BT-20 Dactolisib
3.33
uM
LJP5
 2
M14
 72
hr
 1097 1313 3769 0.3483 0.0807
BT-20 Dactolisib
3.33
uM
LJP5
 3
M14
 72
hr
 1097 1196 3769 0.3173 0.0370
BT-20 NVP-TAE684
3.33
uM
LJP6
 1
K14
 72
hr
 1097 1463 3769 0.3881 0.1369