LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 Imatinib
10.0
uM
LJP6
2
N13
72
hr
1401 4159 4223 0.9848 0.9773
SK-BR-3 Imatinib
10.0
uM
LJP6
3
N13
72
hr
1401 4495 4223 1.0644 1.0964
SK-BR-3 JNK-9L
10.0
uM
LJP6
1
K19
72
hr
1401 1238 4223 0.2932 -0.0580
SK-BR-3 JNK-9L
10.0
uM
LJP6
2
K19
72
hr
1401 1128 4223 0.2671 -0.0969
SK-BR-3 JNK-9L
10.0
uM
LJP6
3
K19
72
hr
1401 1214 4223 0.2875 -0.0665
SK-BR-3 JW-7-24-1
10.0
uM
LJP6
1
B19
72
hr
1401 1221 4223 0.2891 -0.0640
SK-BR-3 JW-7-24-1
10.0
uM
LJP6
2
B19
72
hr
1401 1110 4223 0.2628 -0.1033
SK-BR-3 JW-7-24-1
10.0
uM
LJP6
3
B19
72
hr
1401 1298 4223 0.3074 -0.0367
SK-BR-3 Lapatinib
10.0
uM
LJP6
1
M19
72
hr
1401 1466 4223 0.3471 0.0229
SK-BR-3 Lapatinib
10.0
uM
LJP6
2
M19
72
hr
1401 1987 4223 0.4705 0.2075
SK-BR-3 Lapatinib
10.0
uM
LJP6
3
M19
72
hr
1401 1937 4223 0.4587 0.1898
SK-BR-3 LDN-193189
10.0
uM
LJP5
1
G01
72
hr
1401 227 4223 0.0538 -0.4163
SK-BR-3 LDN-193189
10.0
uM
LJP5
2
G01
72
hr
1401 639 4223 0.1513 -0.2703
SK-BR-3 LDN-193189
10.0
uM
LJP5
3
G01
72
hr
1401 805 4223 0.1906 -0.2114
SK-BR-3 Linifanib
10.0
uM
LJP6
1
J07
72
hr
1401 2017 4223 0.4776 0.2181
SK-BR-3 Linifanib
10.0
uM
LJP6
2
J07
72
hr
1401 2157 4223 0.5108 0.2678
SK-BR-3 Linifanib
10.0
uM
LJP6
3
J07
72
hr
1401 2303 4223 0.5453 0.3195
SK-BR-3 Linsitinib
10.0
uM
LJP5
1
O19
72
hr
1401 2789 4223 0.6604 0.4917
SK-BR-3 Linsitinib
10.0
uM
LJP5
2
O19
72
hr
1401 3077 4223 0.7286 0.5938
SK-BR-3 Linsitinib
10.0
uM
LJP5
3
O19
72
hr
1401 3359 4223 0.7954 0.6938
SK-BR-3 Mitoxantrone
10.0
uM
LJP5
1
C19
72
hr
1401 80 4223 0.0189 -0.4684
SK-BR-3 Mitoxantrone
10.0
uM
LJP5
2
C19
72
hr
1401 122 4223 0.0289 -0.4535
SK-BR-3 Mitoxantrone
10.0
uM
LJP5
3
C19
72
hr
1401 73 4223 0.0173 -0.4709
SK-BR-3 Mitoxantrone
10.0
uM
LJP6
1
C19
72
hr
1401 94 4223 0.0223 -0.4634
SK-BR-3 Mitoxantrone
10.0
uM
LJP6
2
C19
72
hr
1401 94 4223 0.0223 -0.4634