LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 Torin1
0.12
uM
LJP6
3
O17
72
hr
1401 1742 4223 0.4125 0.1207
SK-BR-3 Torin2
0.12
uM
LJP5
1
I23
72
hr
1401 1226 4223 0.2903 -0.0622
SK-BR-3 Torin2
0.12
uM
LJP5
2
I23
72
hr
1401 1450 4223 0.3434 0.0172
SK-BR-3 Torin2
0.12
uM
LJP5
3
I23
72
hr
1401 1254 4223 0.2969 -0.0523
SK-BR-3 Tozasertib
0.12
uM
LJP5
1
B17
72
hr
1401 1248 4223 0.2955 -0.0544
SK-BR-3 Tozasertib
0.12
uM
LJP5
2
B17
72
hr
1401 1315 4223 0.3114 -0.0307
SK-BR-3 Tozasertib
0.12
uM
LJP5
3
B17
72
hr
1401 1375 4223 0.3256 -0.0094
SK-BR-3 Trametinib
0.12
uM
LJP5
1
P23
72
hr
1401 2877 4223 0.6813 0.5229
SK-BR-3 Trametinib
0.12
uM
LJP5
2
P23
72
hr
1401 3256 4223 0.7710 0.6573
SK-BR-3 Trametinib
0.12
uM
LJP5
3
P23
72
hr
1401 3663 4223 0.8674 0.8015
SK-BR-3 TWS119
0.12
uM
LJP5
1
M05
72
hr
1401 4159 4223 0.9848 0.9773
SK-BR-3 TWS119
0.12
uM
LJP5
2
M05
72
hr
1401 4431 4223 1.0492 1.0737
SK-BR-3 TWS119
0.12
uM
LJP5
3
M05
72
hr
1401 4827 4223 1.1430 1.2140
SK-BR-3 Vemurafenib
0.12
uM
LJP5
1
C17
72
hr
1401 4107 4223 0.9725 0.9589
SK-BR-3 Vemurafenib
0.12
uM
LJP5
2
C17
72
hr
1401 4621 4223 1.0942 1.1410
SK-BR-3 Vemurafenib
0.12
uM
LJP5
3
C17
72
hr
1401 4296 4223 1.0173 1.0258
SK-BR-3 Withaferin A
0.12
uM
LJP5
1
G17
72
hr
1401 4183 4223 0.9905 0.9858
SK-BR-3 Withaferin A
0.12
uM
LJP5
2
G17
72
hr
1401 4574 4223 1.0831 1.1244
SK-BR-3 Withaferin A
0.12
uM
LJP5
3
G17
72
hr
1401 4792 4223 1.1347 1.2016
SK-BR-3 Withaferin A
0.12
uM
LJP6
1
G17
72
hr
1401 3621 4223 0.8574 0.7866
SK-BR-3 Withaferin A
0.12
uM
LJP6
2
G17
72
hr
1401 3798 4223 0.8993 0.8493
SK-BR-3 Withaferin A
0.12
uM
LJP6
3
G17
72
hr
1401 3746 4223 0.8870 0.8309
SK-BR-3 WYE-125132
0.12
uM
LJP6
1
L11
72
hr
1401 1687 4223 0.3995 0.1012
SK-BR-3 WYE-125132
0.12
uM
LJP6
2
L11
72
hr
1401 1546 4223 0.3661 0.0512
SK-BR-3 WYE-125132
0.12
uM
LJP6
3
L11
72
hr
1401 1714 4223 0.4059 0.1107