LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 XL147
0.12
uM
LJP5
2
G11
72
hr
1401 4452 4223 1.0542 1.0811
SK-BR-3 XL147
0.12
uM
LJP5
3
G11
72
hr
1401 4803 4223 1.1373 1.2055
SK-BR-3 Saracatinib
0.12
uM
LJP6
1
D11
72
hr
1401 4333 4223 1.0260 1.0390
SK-BR-3 Saracatinib
0.12
uM
LJP6
2
D11
72
hr
1401 4418 4223 1.0462 1.0691
SK-BR-3 Saracatinib
0.12
uM
LJP6
3
D11
72
hr
1401 4809 4223 1.1387 1.2077
SK-BR-3 Selumetinib
0.12
uM
LJP6
1
M11
72
hr
1401 4430 4223 1.0490 1.0733
SK-BR-3 Selumetinib
0.12
uM
LJP6
2
M11
72
hr
1401 4200 4223 0.9945 0.9918
SK-BR-3 Selumetinib
0.12
uM
LJP6
3
M11
72
hr
1401 4321 4223 1.0232 1.0347
SK-BR-3 Sirolimus
0.12
uM
LJP6
1
L17
72
hr
1401 2781 4223 0.6585 0.4889
SK-BR-3 Sirolimus
0.12
uM
LJP6
2
L17
72
hr
1401 2556 4223 0.6052 0.4092
SK-BR-3 Sirolimus
0.12
uM
LJP6
3
L17
72
hr
1401 2720 4223 0.6441 0.4673
SK-BR-3 Sorafenib
0.12
uM
LJP6
1
B11
72
hr
1401 3938 4223 0.9325 0.8990
SK-BR-3 Sorafenib
0.12
uM
LJP6
2
B11
72
hr
1401 4229 4223 1.0014 1.0021
SK-BR-3 Sorafenib
0.12
uM
LJP6
3
B11
72
hr
1401 3962 4223 0.9382 0.9075
SK-BR-3 SU11274
0.12
uM
LJP5
1
J11
72
hr
1401 3926 4223 0.9297 0.8947
SK-BR-3 SU11274
0.12
uM
LJP5
2
J11
72
hr
1401 4048 4223 0.9585 0.9380
SK-BR-3 SU11274
0.12
uM
LJP5
3
J11
72
hr
1401 4792 4223 1.1347 1.2016
SK-BR-3 Fedratinib
0.12
uM
LJP5
1
L05
72
hr
1401 3963 4223 0.9384 0.9078
SK-BR-3 Fedratinib
0.12
uM
LJP5
2
L05
72
hr
1401 4191 4223 0.9924 0.9886
SK-BR-3 Fedratinib
0.12
uM
LJP5
3
L05
72
hr
1401 4525 4223 1.0715 1.1070
SK-BR-3 TGX221
0.12
uM
LJP5
1
H23
72
hr
1401 3285 4223 0.7779 0.6675
SK-BR-3 TGX221
0.12
uM
LJP5
2
H23
72
hr
1401 3668 4223 0.8686 0.8033
SK-BR-3 TGX221
0.12
uM
LJP5
3
H23
72
hr
1401 4281 4223 1.0137 1.0205
SK-BR-3 Torin1
0.12
uM
LJP6
1
O17
72
hr
1401 1689 4223 0.3999 0.1019
SK-BR-3 Torin1
0.12
uM
LJP6
2
O17
72
hr
1401 1742 4223 0.4125 0.1207