LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SK-BR-3 | XL147 | 0.12 | uM | LJP5 | 2 | G11 | 72 | hr | 1401 | 4452 | 4223 | 1.0542 | 1.0811 |
SK-BR-3 | XL147 | 0.12 | uM | LJP5 | 3 | G11 | 72 | hr | 1401 | 4803 | 4223 | 1.1373 | 1.2055 |
SK-BR-3 | Saracatinib | 0.12 | uM | LJP6 | 1 | D11 | 72 | hr | 1401 | 4333 | 4223 | 1.0260 | 1.0390 |
SK-BR-3 | Saracatinib | 0.12 | uM | LJP6 | 2 | D11 | 72 | hr | 1401 | 4418 | 4223 | 1.0462 | 1.0691 |
SK-BR-3 | Saracatinib | 0.12 | uM | LJP6 | 3 | D11 | 72 | hr | 1401 | 4809 | 4223 | 1.1387 | 1.2077 |
SK-BR-3 | Selumetinib | 0.12 | uM | LJP6 | 1 | M11 | 72 | hr | 1401 | 4430 | 4223 | 1.0490 | 1.0733 |
SK-BR-3 | Selumetinib | 0.12 | uM | LJP6 | 2 | M11 | 72 | hr | 1401 | 4200 | 4223 | 0.9945 | 0.9918 |
SK-BR-3 | Selumetinib | 0.12 | uM | LJP6 | 3 | M11 | 72 | hr | 1401 | 4321 | 4223 | 1.0232 | 1.0347 |
SK-BR-3 | Sirolimus | 0.12 | uM | LJP6 | 1 | L17 | 72 | hr | 1401 | 2781 | 4223 | 0.6585 | 0.4889 |
SK-BR-3 | Sirolimus | 0.12 | uM | LJP6 | 2 | L17 | 72 | hr | 1401 | 2556 | 4223 | 0.6052 | 0.4092 |
SK-BR-3 | Sirolimus | 0.12 | uM | LJP6 | 3 | L17 | 72 | hr | 1401 | 2720 | 4223 | 0.6441 | 0.4673 |
SK-BR-3 | Sorafenib | 0.12 | uM | LJP6 | 1 | B11 | 72 | hr | 1401 | 3938 | 4223 | 0.9325 | 0.8990 |
SK-BR-3 | Sorafenib | 0.12 | uM | LJP6 | 2 | B11 | 72 | hr | 1401 | 4229 | 4223 | 1.0014 | 1.0021 |
SK-BR-3 | Sorafenib | 0.12 | uM | LJP6 | 3 | B11 | 72 | hr | 1401 | 3962 | 4223 | 0.9382 | 0.9075 |
SK-BR-3 | SU11274 | 0.12 | uM | LJP5 | 1 | J11 | 72 | hr | 1401 | 3926 | 4223 | 0.9297 | 0.8947 |
SK-BR-3 | SU11274 | 0.12 | uM | LJP5 | 2 | J11 | 72 | hr | 1401 | 4048 | 4223 | 0.9585 | 0.9380 |
SK-BR-3 | SU11274 | 0.12 | uM | LJP5 | 3 | J11 | 72 | hr | 1401 | 4792 | 4223 | 1.1347 | 1.2016 |
SK-BR-3 | Fedratinib | 0.12 | uM | LJP5 | 1 | L05 | 72 | hr | 1401 | 3963 | 4223 | 0.9384 | 0.9078 |
SK-BR-3 | Fedratinib | 0.12 | uM | LJP5 | 2 | L05 | 72 | hr | 1401 | 4191 | 4223 | 0.9924 | 0.9886 |
SK-BR-3 | Fedratinib | 0.12 | uM | LJP5 | 3 | L05 | 72 | hr | 1401 | 4525 | 4223 | 1.0715 | 1.1070 |
SK-BR-3 | TGX221 | 0.12 | uM | LJP5 | 1 | H23 | 72 | hr | 1401 | 3285 | 4223 | 0.7779 | 0.6675 |
SK-BR-3 | TGX221 | 0.12 | uM | LJP5 | 2 | H23 | 72 | hr | 1401 | 3668 | 4223 | 0.8686 | 0.8033 |
SK-BR-3 | TGX221 | 0.12 | uM | LJP5 | 3 | H23 | 72 | hr | 1401 | 4281 | 4223 | 1.0137 | 1.0205 |
SK-BR-3 | Torin1 | 0.12 | uM | LJP6 | 1 | O17 | 72 | hr | 1401 | 1689 | 4223 | 0.3999 | 0.1019 |
SK-BR-3 | Torin1 | 0.12 | uM | LJP6 | 2 | O17 | 72 | hr | 1401 | 1742 | 4223 | 0.4125 | 0.1207 |