LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | WZ3105 | 0.12 | uM | LJP5 | 1 | D23 | 72 | hr | 1401 | 766 | 4223 | 0.1814 | -0.2252 |
| SK-BR-3 | WZ3105 | 0.12 | uM | LJP5 | 2 | D23 | 72 | hr | 1401 | 989 | 4223 | 0.2342 | -0.1462 |
| SK-BR-3 | WZ3105 | 0.12 | uM | LJP5 | 3 | D23 | 72 | hr | 1401 | 860 | 4223 | 0.2036 | -0.1919 |
| SK-BR-3 | XMD11-50 | 0.12 | uM | LJP6 | 1 | P11 | 72 | hr | 1401 | 3709 | 4223 | 0.8783 | 0.8178 |
| SK-BR-3 | XMD11-50 | 0.12 | uM | LJP6 | 2 | P11 | 72 | hr | 1401 | 3526 | 4223 | 0.8349 | 0.7529 |
| SK-BR-3 | XMD11-50 | 0.12 | uM | LJP6 | 3 | P11 | 72 | hr | 1401 | 3323 | 4223 | 0.7869 | 0.6810 |
| SK-BR-3 | Y39983 | 0.12 | uM | LJP6 | 1 | P05 | 72 | hr | 1401 | 4042 | 4223 | 0.9571 | 0.9358 |
| SK-BR-3 | Y39983 | 0.12 | uM | LJP6 | 2 | P05 | 72 | hr | 1401 | 4238 | 4223 | 1.0035 | 1.0053 |
| SK-BR-3 | Y39983 | 0.12 | uM | LJP6 | 3 | P05 | 72 | hr | 1401 | 4264 | 4223 | 1.0097 | 1.0145 |
| SK-BR-3 | YM 201636 | 0.12 | uM | LJP5 | 1 | N11 | 72 | hr | 1401 | 4006 | 4223 | 0.9486 | 0.9231 |
| SK-BR-3 | YM 201636 | 0.12 | uM | LJP5 | 2 | N11 | 72 | hr | 1401 | 4541 | 4223 | 1.0753 | 1.1127 |
| SK-BR-3 | YM 201636 | 0.12 | uM | LJP5 | 3 | N11 | 72 | hr | 1401 | 4793 | 4223 | 1.1350 | 1.2020 |
| SK-BR-3 | ZSTK474 | 0.12 | uM | LJP6 | 1 | M17 | 72 | hr | 1401 | 2408 | 4223 | 0.5702 | 0.3567 |
| SK-BR-3 | ZSTK474 | 0.12 | uM | LJP6 | 2 | M17 | 72 | hr | 1401 | 2350 | 4223 | 0.5565 | 0.3362 |
| SK-BR-3 | ZSTK474 | 0.12 | uM | LJP6 | 3 | M17 | 72 | hr | 1401 | 2356 | 4223 | 0.5579 | 0.3383 |
| SK-BR-3 | Afatinib | 0.37 | uM | LJP6 | 1 | G22 | 72 | hr | 1401 | 1484 | 4223 | 0.3514 | 0.0292 |
| SK-BR-3 | Afatinib | 0.37 | uM | LJP6 | 2 | G22 | 72 | hr | 1401 | 1450 | 4223 | 0.3434 | 0.0172 |
| SK-BR-3 | Afatinib | 0.37 | uM | LJP6 | 3 | G22 | 72 | hr | 1401 | 1269 | 4223 | 0.3005 | -0.0470 |
| SK-BR-3 | Sigma A6730 | 0.37 | uM | LJP5 | 1 | B22 | 72 | hr | 1401 | 3313 | 4223 | 0.7845 | 0.6775 |
| SK-BR-3 | Sigma A6730 | 0.37 | uM | LJP5 | 2 | B22 | 72 | hr | 1401 | 3478 | 4223 | 0.8236 | 0.7359 |
| SK-BR-3 | Sigma A6730 | 0.37 | uM | LJP5 | 3 | B22 | 72 | hr | 1401 | 3886 | 4223 | 0.9202 | 0.8805 |
| SK-BR-3 | Alvocidib | 0.37 | uM | LJP6 | 1 | A16 | 72 | hr | 1401 | 1025 | 4223 | 0.2427 | -0.1335 |
| SK-BR-3 | Alvocidib | 0.37 | uM | LJP6 | 2 | A16 | 72 | hr | 1401 | 889 | 4223 | 0.2105 | -0.1817 |
| SK-BR-3 | Alvocidib | 0.37 | uM | LJP6 | 3 | A16 | 72 | hr | 1401 | 965 | 4223 | 0.2285 | -0.1547 |
| SK-BR-3 | AT-7519 | 0.37 | uM | LJP6 | 1 | K04 | 72 | hr | 1401 | 1110 | 4223 | 0.2628 | -0.1033 |