LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Pictilisib
3.33
uM
LJP6
 3
D20
 72
hr
 1235 3058 4513 0.6775 0.5559
MDA-MB-231 Gefitinib
3.33
uM
LJP6
 1
N08
 72
hr
 1235 4115 4513 0.9117 0.8784
MDA-MB-231 Gefitinib
3.33
uM
LJP6
 2
N08
 72
hr
 1235 4256 4513 0.9429 0.9214
MDA-MB-231 Gefitinib
3.33
uM
LJP6
 3
N08
 72
hr
 1235 4119 4513 0.9126 0.8796
MDA-MB-231 Geldanamycin
3.33
uM
LJP5
 1
O02
 72
hr
 1235 733 4513 0.1624 -0.1535
MDA-MB-231 Geldanamycin
3.33
uM
LJP5
 2
O02
 72
hr
 1235 715 4513 0.1584 -0.1589
MDA-MB-231 Geldanamycin
3.33
uM
LJP5
 3
O02
 72
hr
 1235 782 4513 0.1733 -0.1385
MDA-MB-231 Geldanamycin
3.33
uM
LJP6
 1
O02
 72
hr
 1235 702 4513 0.1555 -0.1629
MDA-MB-231 Geldanamycin
3.33
uM
LJP6
 2
O02
 72
hr
 1235 293 4513 0.0649 -0.2877
MDA-MB-231 Geldanamycin
3.33
uM
LJP6
 3
O02
 72
hr
 1235 794 4513 0.1759 -0.1348
MDA-MB-231 GSK1059615
3.33
uM
LJP5
 1
E02
 72
hr
 1235 1177 4513 0.2608 -0.0180
MDA-MB-231 GSK1059615
3.33
uM
LJP5
 2
E02
 72
hr
 1235 984 4513 0.2180 -0.0769
MDA-MB-231 GSK1059615
3.33
uM
LJP5
 3
E02
 72
hr
 1235 1193 4513 0.2643 -0.0131
MDA-MB-231 GSK1059615
3.33
uM
LJP6
 1
C02
 72
hr
 1235 1175 4513 0.2603 -0.0186
MDA-MB-231 GSK1059615
3.33
uM
LJP6
 2
C02
 72
hr
 1235 576 4513 0.1276 -0.2014
MDA-MB-231 GSK1059615
3.33
uM
LJP6
 3
C02
 72
hr
 1235 1813 4513 0.4017 0.1761
MDA-MB-231 GSK1904529A
3.33
uM
LJP6
 1
H20
 72
hr
 1235 4527 4513 1.0030 1.0041
MDA-MB-231 GSK1904529A
3.33
uM
LJP6
 2
H20
 72
hr
 1235 4296 4513 0.9518 0.9336
MDA-MB-231 GSK1904529A
3.33
uM
LJP6
 3
H20
 72
hr
 1235 4289 4513 0.9502 0.9315
MDA-MB-231 Omipalisib
3.33
uM
LJP6
 1
N02
 72
hr
 1235 805 4513 0.1784 -0.1315
MDA-MB-231 Omipalisib
3.33
uM
LJP6
 2
N02
 72
hr
 1235 826 4513 0.1830 -0.1251
MDA-MB-231 Omipalisib
3.33
uM
LJP6
 3
N02
 72
hr
 1235 842 4513 0.1866 -0.1202
MDA-MB-231 GSK 690693
3.33
uM
LJP5
 1
F20
 72
hr
 1235 4584 4513 1.0156 1.0215
MDA-MB-231 GSK 690693
3.33
uM
LJP5
 2
F20
 72
hr
 1235 4848 4513 1.0741 1.1020
MDA-MB-231 GSK 690693
3.33
uM
LJP5
 3
F20
 72
hr
 1235 5038 4513 1.1162 1.1600