LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | AZD 5438 | 10.0 | uM | LJP6 | 3 | J01 | 72 | hr | 1235 | 337 | 4513 | 0.0747 | -0.2743 |
| MDA-MB-231 | A443654 | 10.0 | uM | LJP6 | 3 | I19 | 72 | hr | 1235 | 337 | 4513 | 0.0747 | -0.2743 |
| MDA-MB-231 | NVP-TAE684 | 10.0 | uM | LJP6 | 3 | K13 | 72 | hr | 1235 | 338 | 4513 | 0.0749 | -0.2740 |
| MDA-MB-231 | BMS345541 | 10.0 | uM | LJP6 | 1 | D01 | 72 | hr | 1235 | 340 | 4513 | 0.0753 | -0.2734 |
| Hs 578T | Omipalisib | 10.0 | uM | LJP6 | 1 | N01 | 72 | hr | 658 | 340 | 3846 | 0.0884 | -0.0998 |
| MCF 10A | PHA-793887 | 10.0 | uM | LJP6 | 3 | E19 | 72 | hr | 962 | 341 | 10605 | 0.0322 | -0.0644 |
| BT-20 | Geldanamycin | 10.0 | uM | LJP5 | 1 | O01 | 72 | hr | 1097 | 341 | 3769 | 0.0905 | -0.2830 |
| Hs 578T | Withaferin A | 10.0 | uM | LJP6 | 3 | G13 | 72 | hr | 658 | 342 | 3846 | 0.0889 | -0.0992 |
| MDA-MB-231 | CGP60474 | 10.0 | uM | LJP6 | 1 | G01 | 72 | hr | 1235 | 343 | 4513 | 0.0760 | -0.2724 |
| MDA-MB-231 | A443654 | 10.0 | uM | LJP6 | 2 | I19 | 72 | hr | 1235 | 345 | 4513 | 0.0764 | -0.2718 |
| MCF 10A | PF562271 | 10.0 | uM | LJP6 | 1 | F13 | 72 | hr | 962 | 345 | 10605 | 0.0325 | -0.0640 |
| Hs 578T | Omipalisib | 10.0 | uM | LJP6 | 3 | N01 | 72 | hr | 658 | 347 | 3846 | 0.0902 | -0.0976 |
| MDA-MB-231 | Geldanamycin | 10.0 | uM | LJP6 | 1 | O01 | 72 | hr | 1235 | 347 | 4513 | 0.0769 | -0.2712 |
| Hs 578T | CGP60474 | 10.0 | uM | LJP5 | 3 | F01 | 72 | hr | 658 | 348 | 3846 | 0.0905 | -0.0973 |
| MCF 10A | Celastrol | 3.33 | uM | LJP6 | 3 | G08 | 72 | hr | 962 | 349 | 10605 | 0.0329 | -0.0636 |
| SK-BR-3 | AT-7519 | 10.0 | uM | LJP6 | 1 | K01 | 72 | hr | 1401 | 349 | 4223 | 0.0826 | -0.3730 |
| Hs 578T | Fedratinib | 10.0 | uM | LJP5 | 3 | L01 | 72 | hr | 658 | 349 | 3846 | 0.0907 | -0.0970 |
| BT-20 | LDN-193189 | 3.33 | uM | LJP5 | 2 | G02 | 72 | hr | 1097 | 350 | 3769 | 0.0929 | -0.2796 |
| MDA-MB-231 | A443654 | 10.0 | uM | LJP6 | 1 | I19 | 72 | hr | 1235 | 350 | 4513 | 0.0775 | -0.2703 |
| Hs 578T | A443654 | 0.37 | uM | LJP6 | 2 | I22 | 72 | hr | 658 | 351 | 3846 | 0.0913 | -0.0964 |
| MDA-MB-231 | PHA-793887 | 10.0 | uM | LJP6 | 1 | E19 | 72 | hr | 1235 | 351 | 4513 | 0.0778 | -0.2700 |
| Hs 578T | Fedratinib | 10.0 | uM | LJP5 | 1 | L01 | 72 | hr | 658 | 352 | 3846 | 0.0915 | -0.0960 |
| Hs 578T | CGP60474 | 3.33 | uM | LJP5 | 2 | F02 | 72 | hr | 658 | 352 | 3846 | 0.0915 | -0.0960 |
| MDA-MB-231 | AT-7519 | 10.0 | uM | LJP6 | 3 | K01 | 72 | hr | 1235 | 352 | 4513 | 0.0780 | -0.2697 |
| MCF7 | JNK-9L | 3.33 | uM | LJP6 | 2 | K20 | 72 | hr | 1209 | 355 | 4093 | 0.0867 | -0.2964 |