LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Ruxolitinib | 3.33 | uM | LJP5 | 2 | O14 | 72 | hr | 1209 | 4880 | 4093 | 1.1923 | 1.2729 |
| BT-20 | Enzastaurin | 10.0 | uM | LJP5 | 2 | D13 | 72 | hr | 1097 | 4498 | 3769 | 1.1932 | 1.2726 |
| SK-BR-3 | TWS119 | 0.04 | uM | LJP5 | 1 | M06 | 72 | hr | 1401 | 5060 | 4223 | 1.1982 | 1.2966 |
| SK-BR-3 | Enzastaurin | 0.37 | uM | LJP5 | 2 | D16 | 72 | hr | 1401 | 5062 | 4223 | 1.1986 | 1.2973 |
| MDA-MB-231 | Enzastaurin | 10.0 | uM | LJP5 | 3 | D13 | 72 | hr | 1235 | 5417 | 4513 | 1.2001 | 1.2756 |
| MDA-MB-231 | PD173074 | 0.37 | uM | LJP6 | 2 | I10 | 72 | hr | 1235 | 5433 | 4513 | 1.2037 | 1.2805 |
| BT-20 | YM 201636 | 0.04 | uM | LJP5 | 2 | N12 | 72 | hr | 1097 | 4561 | 3769 | 1.2100 | 1.2962 |
| MCF7 | SU11274 | 0.04 | uM | LJP5 | 3 | J12 | 72 | hr | 1209 | 4955 | 4093 | 1.2106 | 1.2989 |
| SK-BR-3 | Nilotinib | 1.11 | uM | LJP5 | 3 | N15 | 72 | hr | 1401 | 5113 | 4223 | 1.2107 | 1.3154 |
| BT-20 | XL147 | 0.04 | uM | LJP5 | 3 | G12 | 72 | hr | 1097 | 4581 | 3769 | 1.2153 | 1.3037 |
| SK-BR-3 | SB590885 | 3.33 | uM | LJP5 | 3 | L14 | 72 | hr | 1401 | 5140 | 4223 | 1.2171 | 1.3250 |
| SK-BR-3 | CP466722 | 0.37 | uM | LJP5 | 1 | I10 | 72 | hr | 1401 | 5159 | 4223 | 1.2216 | 1.3317 |
| SK-BR-3 | XL147 | 3.33 | uM | LJP5 | 1 | G08 | 72 | hr | 1401 | 5165 | 4223 | 1.2230 | 1.3338 |
| BT-20 | Enzastaurin | 10.0 | uM | LJP5 | 3 | D13 | 72 | hr | 1097 | 4613 | 3769 | 1.2238 | 1.3156 |
| SK-BR-3 | XL147 | 0.12 | uM | LJP5 | 1 | G11 | 72 | hr | 1401 | 5210 | 4223 | 1.2337 | 1.3498 |
| SK-BR-3 | Nilotinib | 0.37 | uM | LJP5 | 3 | N16 | 72 | hr | 1401 | 5264 | 4223 | 1.2465 | 1.3689 |
| BT-20 | Enzastaurin | 3.33 | uM | LJP5 | 3 | D14 | 72 | hr | 1097 | 4707 | 3769 | 1.2487 | 1.3508 |
| SK-BR-3 | Nilotinib | 0.12 | uM | LJP5 | 3 | N17 | 72 | hr | 1401 | 5276 | 4223 | 1.2493 | 1.3732 |
| SK-BR-3 | CP466722 | 0.04 | uM | LJP5 | 1 | I12 | 72 | hr | 1401 | 5290 | 4223 | 1.2526 | 1.3781 |
| SK-BR-3 | XL147 | 0.37 | uM | LJP5 | 1 | G10 | 72 | hr | 1401 | 5312 | 4223 | 1.2578 | 1.3859 |