LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Mitoxantrone | 10.0 | uM | LJP6 | 1 | C19 | 72 | hr | 1209 | 69 | 4093 | 0.0169 | -0.3956 |
| MCF 10A | WZ3105 | 3.33 | uM | LJP5 | 1 | D20 | 72 | hr | 962 | 180 | 10605 | 0.0170 | -0.0811 |
| MCF 10A | AT-7519 | 3.33 | uM | LJP6 | 3 | K02 | 72 | hr | 962 | 181 | 10605 | 0.0171 | -0.0810 |
| SK-BR-3 | Mitoxantrone | 10.0 | uM | LJP5 | 3 | C19 | 72 | hr | 1401 | 73 | 4223 | 0.0173 | -0.4709 |
| MCF 10A | Torin2 | 0.04 | uM | LJP5 | 2 | I24 | 72 | hr | 962 | 189 | 10605 | 0.0178 | -0.0802 |
| MCF7 | Mitoxantrone | 10.0 | uM | LJP6 | 3 | C19 | 72 | hr | 1209 | 73 | 4093 | 0.0178 | -0.3942 |
| MCF 10A | Alvocidib | 0.37 | uM | LJP6 | 3 | A16 | 72 | hr | 962 | 189 | 10605 | 0.0178 | -0.0802 |
| MCF 10A | AT-7519 | 10.0 | uM | LJP6 | 1 | K01 | 72 | hr | 962 | 193 | 10605 | 0.0182 | -0.0798 |
| MCF 10A | Canertinib | 10.0 | uM | LJP6 | 2 | H07 | 72 | hr | 962 | 193 | 10605 | 0.0182 | -0.0798 |
| MCF 10A | AT-7519 | 3.33 | uM | LJP6 | 2 | K02 | 72 | hr | 962 | 195 | 10605 | 0.0184 | -0.0796 |
| MCF 10A | SNS-032 | 3.33 | uM | LJP6 | 1 | H14 | 72 | hr | 962 | 196 | 10605 | 0.0185 | -0.0795 |
| MCF 10A | Alvocidib | 0.37 | uM | LJP6 | 2 | A16 | 72 | hr | 962 | 197 | 10605 | 0.0186 | -0.0793 |
| MCF 10A | Alvocidib | 1.11 | uM | LJP6 | 3 | A15 | 72 | hr | 962 | 197 | 10605 | 0.0186 | -0.0793 |
| MCF 10A | Alvocidib | 1.11 | uM | LJP6 | 1 | A15 | 72 | hr | 962 | 198 | 10605 | 0.0187 | -0.0792 |
| SK-BR-3 | Mitoxantrone | 10.0 | uM | LJP5 | 1 | C19 | 72 | hr | 1401 | 80 | 4223 | 0.0189 | -0.4684 |
| MCF7 | Mitoxantrone | 10.0 | uM | LJP5 | 2 | C19 | 72 | hr | 1209 | 78 | 4093 | 0.0191 | -0.3924 |
| MCF 10A | CGP60474 | 3.33 | uM | LJP6 | 1 | G02 | 72 | hr | 962 | 204 | 10605 | 0.0192 | -0.0786 |
| MCF 10A | AT-7519 | 3.33 | uM | LJP6 | 1 | K02 | 72 | hr | 962 | 206 | 10605 | 0.0194 | -0.0784 |
| MDA-MB-231 | Mitoxantrone | 10.0 | uM | LJP5 | 3 | C19 | 72 | hr | 1235 | 88 | 4513 | 0.0195 | -0.3502 |
| MCF 10A | CGP60474 | 1.11 | uM | LJP5 | 3 | F03 | 72 | hr | 962 | 211 | 10605 | 0.0199 | -0.0779 |
| MCF 10A | Canertinib | 10.0 | uM | LJP6 | 1 | H07 | 72 | hr | 962 | 212 | 10605 | 0.0200 | -0.0778 |
| MCF 10A | Alvocidib | 3.33 | uM | LJP6 | 1 | A14 | 72 | hr | 962 | 212 | 10605 | 0.0200 | -0.0778 |
| MCF 10A | Alvocidib | 0.37 | uM | LJP6 | 1 | A16 | 72 | hr | 962 | 215 | 10605 | 0.0203 | -0.0775 |
| MCF 10A | A443654 | 10.0 | uM | LJP6 | 2 | I19 | 72 | hr | 962 | 216 | 10605 | 0.0204 | -0.0774 |
| MCF 10A | CGP60474 | 3.33 | uM | LJP6 | 2 | G02 | 72 | hr | 962 | 217 | 10605 | 0.0205 | -0.0773 |