LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
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BT-20 | Seliciclib | 0.04 | uM | LJP5 | 3 | J06 | 72 | hr | 1097 | 3831 | 3769 | 1.0163 | 1.0230 |
BT-20 | Ruxolitinib | 0.04 | uM | LJP5 | 1 | O18 | 72 | hr | 1097 | 3651 | 3769 | 0.9686 | 0.9556 |
BT-20 | Ruxolitinib | 0.04 | uM | LJP5 | 2 | O18 | 72 | hr | 1097 | 3436 | 3769 | 0.9115 | 0.8752 |
BT-20 | Ruxolitinib | 0.04 | uM | LJP5 | 3 | O18 | 72 | hr | 1097 | 3975 | 3769 | 1.0545 | 1.0769 |
BT-20 | XL147 | 0.04 | uM | LJP5 | 1 | G12 | 72 | hr | 1097 | 4110 | 3769 | 1.0903 | 1.1274 |
BT-20 | XL147 | 0.04 | uM | LJP5 | 2 | G12 | 72 | hr | 1097 | 4215 | 3769 | 1.1182 | 1.1667 |
BT-20 | XL147 | 0.04 | uM | LJP5 | 3 | G12 | 72 | hr | 1097 | 4581 | 3769 | 1.2153 | 1.3037 |
BT-20 | Saracatinib | 0.04 | uM | LJP6 | 1 | D12 | 72 | hr | 1097 | 3604 | 3769 | 0.9561 | 0.9381 |
BT-20 | Saracatinib | 0.04 | uM | LJP6 | 2 | D12 | 72 | hr | 1097 | 3541 | 3769 | 0.9394 | 0.9145 |
BT-20 | Saracatinib | 0.04 | uM | LJP6 | 3 | D12 | 72 | hr | 1097 | 3354 | 3769 | 0.8898 | 0.8445 |
BT-20 | Selumetinib | 0.04 | uM | LJP6 | 1 | M12 | 72 | hr | 1097 | 3597 | 3769 | 0.9542 | 0.9354 |
BT-20 | Selumetinib | 0.04 | uM | LJP6 | 2 | M12 | 72 | hr | 1097 | 3837 | 3769 | 1.0179 | 1.0252 |
BT-20 | Selumetinib | 0.04 | uM | LJP6 | 3 | M12 | 72 | hr | 1097 | 3694 | 3769 | 0.9800 | 0.9717 |
BT-20 | Sirolimus | 0.04 | uM | LJP6 | 1 | L18 | 72 | hr | 1097 | 2342 | 3769 | 0.6213 | 0.4658 |
BT-20 | Sirolimus | 0.04 | uM | LJP6 | 2 | L18 | 72 | hr | 1097 | 2241 | 3769 | 0.5945 | 0.4280 |
BT-20 | Sirolimus | 0.04 | uM | LJP6 | 3 | L18 | 72 | hr | 1097 | 2519 | 3769 | 0.6683 | 0.5320 |
BT-20 | Sorafenib | 0.04 | uM | LJP6 | 1 | B12 | 72 | hr | 1097 | 3425 | 3769 | 0.9086 | 0.8711 |
BT-20 | Sorafenib | 0.04 | uM | LJP6 | 2 | B12 | 72 | hr | 1097 | 3511 | 3769 | 0.9314 | 0.9033 |
BT-20 | Sorafenib | 0.04 | uM | LJP6 | 3 | B12 | 72 | hr | 1097 | 3299 | 3769 | 0.8752 | 0.8239 |
BT-20 | SU11274 | 0.04 | uM | LJP5 | 1 | J12 | 72 | hr | 1097 | 4265 | 3769 | 1.1314 | 1.1854 |
BT-20 | SU11274 | 0.04 | uM | LJP5 | 2 | J12 | 72 | hr | 1097 | 3959 | 3769 | 1.0503 | 1.0709 |
BT-20 | SU11274 | 0.04 | uM | LJP5 | 3 | J12 | 72 | hr | 1097 | 4270 | 3769 | 1.1328 | 1.1873 |
BT-20 | Fedratinib | 0.04 | uM | LJP5 | 1 | L06 | 72 | hr | 1097 | 4162 | 3769 | 1.1041 | 1.1469 |
BT-20 | Fedratinib | 0.04 | uM | LJP5 | 2 | L06 | 72 | hr | 1097 | 4023 | 3769 | 1.0672 | 1.0948 |
BT-20 | Fedratinib | 0.04 | uM | LJP5 | 3 | L06 | 72 | hr | 1097 | 4135 | 3769 | 1.0970 | 1.1368 |