LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 Seliciclib
0.04
uM
LJP5
3
J06
72
hr
1097 3831 3769 1.0163 1.0230
BT-20 Ruxolitinib
0.04
uM
LJP5
1
O18
72
hr
1097 3651 3769 0.9686 0.9556
BT-20 Ruxolitinib
0.04
uM
LJP5
2
O18
72
hr
1097 3436 3769 0.9115 0.8752
BT-20 Ruxolitinib
0.04
uM
LJP5
3
O18
72
hr
1097 3975 3769 1.0545 1.0769
BT-20 XL147
0.04
uM
LJP5
1
G12
72
hr
1097 4110 3769 1.0903 1.1274
BT-20 XL147
0.04
uM
LJP5
2
G12
72
hr
1097 4215 3769 1.1182 1.1667
BT-20 XL147
0.04
uM
LJP5
3
G12
72
hr
1097 4581 3769 1.2153 1.3037
BT-20 Saracatinib
0.04
uM
LJP6
1
D12
72
hr
1097 3604 3769 0.9561 0.9381
BT-20 Saracatinib
0.04
uM
LJP6
2
D12
72
hr
1097 3541 3769 0.9394 0.9145
BT-20 Saracatinib
0.04
uM
LJP6
3
D12
72
hr
1097 3354 3769 0.8898 0.8445
BT-20 Selumetinib
0.04
uM
LJP6
1
M12
72
hr
1097 3597 3769 0.9542 0.9354
BT-20 Selumetinib
0.04
uM
LJP6
2
M12
72
hr
1097 3837 3769 1.0179 1.0252
BT-20 Selumetinib
0.04
uM
LJP6
3
M12
72
hr
1097 3694 3769 0.9800 0.9717
BT-20 Sirolimus
0.04
uM
LJP6
1
L18
72
hr
1097 2342 3769 0.6213 0.4658
BT-20 Sirolimus
0.04
uM
LJP6
2
L18
72
hr
1097 2241 3769 0.5945 0.4280
BT-20 Sirolimus
0.04
uM
LJP6
3
L18
72
hr
1097 2519 3769 0.6683 0.5320
BT-20 Sorafenib
0.04
uM
LJP6
1
B12
72
hr
1097 3425 3769 0.9086 0.8711
BT-20 Sorafenib
0.04
uM
LJP6
2
B12
72
hr
1097 3511 3769 0.9314 0.9033
BT-20 Sorafenib
0.04
uM
LJP6
3
B12
72
hr
1097 3299 3769 0.8752 0.8239
BT-20 SU11274
0.04
uM
LJP5
1
J12
72
hr
1097 4265 3769 1.1314 1.1854
BT-20 SU11274
0.04
uM
LJP5
2
J12
72
hr
1097 3959 3769 1.0503 1.0709
BT-20 SU11274
0.04
uM
LJP5
3
J12
72
hr
1097 4270 3769 1.1328 1.1873
BT-20 Fedratinib
0.04
uM
LJP5
1
L06
72
hr
1097 4162 3769 1.1041 1.1469
BT-20 Fedratinib
0.04
uM
LJP5
2
L06
72
hr
1097 4023 3769 1.0672 1.0948
BT-20 Fedratinib
0.04
uM
LJP5
3
L06
72
hr
1097 4135 3769 1.0970 1.1368