LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
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BT-20 | TGX221 | 0.04 | uM | LJP5 | 1 | H24 | 72 | hr | 1097 | 3732 | 3769 | 0.9900 | 0.9860 |
BT-20 | TGX221 | 0.04 | uM | LJP5 | 2 | H24 | 72 | hr | 1097 | 3583 | 3769 | 0.9505 | 0.9302 |
BT-20 | TGX221 | 0.04 | uM | LJP5 | 3 | H24 | 72 | hr | 1097 | 3742 | 3769 | 0.9927 | 0.9897 |
BT-20 | Torin1 | 0.04 | uM | LJP6 | 1 | O18 | 72 | hr | 1097 | 1487 | 3769 | 0.3945 | 0.1459 |
BT-20 | Torin1 | 0.04 | uM | LJP6 | 2 | O18 | 72 | hr | 1097 | 1501 | 3769 | 0.3982 | 0.1511 |
BT-20 | Torin1 | 0.04 | uM | LJP6 | 3 | O18 | 72 | hr | 1097 | 1555 | 3769 | 0.4125 | 0.1713 |
BT-20 | Torin2 | 0.04 | uM | LJP5 | 1 | I24 | 72 | hr | 1097 | 996 | 3769 | 0.2642 | -0.0379 |
BT-20 | Torin2 | 0.04 | uM | LJP5 | 2 | I24 | 72 | hr | 1097 | 934 | 3769 | 0.2478 | -0.0611 |
BT-20 | Torin2 | 0.04 | uM | LJP5 | 3 | I24 | 72 | hr | 1097 | 977 | 3769 | 0.2592 | -0.0450 |
BT-20 | Tozasertib | 0.04 | uM | LJP5 | 1 | B18 | 72 | hr | 1097 | 1813 | 3769 | 0.4810 | 0.2678 |
BT-20 | Tozasertib | 0.04 | uM | LJP5 | 2 | B18 | 72 | hr | 1097 | 1992 | 3769 | 0.5285 | 0.3348 |
BT-20 | Tozasertib | 0.04 | uM | LJP5 | 3 | B18 | 72 | hr | 1097 | 2278 | 3769 | 0.6043 | 0.4419 |
BT-20 | Trametinib | 0.04 | uM | LJP5 | 1 | P24 | 72 | hr | 1097 | 2687 | 3769 | 0.7128 | 0.5949 |
BT-20 | Trametinib | 0.04 | uM | LJP5 | 2 | P24 | 72 | hr | 1097 | 3198 | 3769 | 0.8484 | 0.7861 |
BT-20 | Trametinib | 0.04 | uM | LJP5 | 3 | P24 | 72 | hr | 1097 | 3250 | 3769 | 0.8622 | 0.8056 |
BT-20 | TWS119 | 0.04 | uM | LJP5 | 1 | M06 | 72 | hr | 1097 | 3697 | 3769 | 0.9808 | 0.9729 |
BT-20 | TWS119 | 0.04 | uM | LJP5 | 2 | M06 | 72 | hr | 1097 | 3995 | 3769 | 1.0598 | 1.0844 |
BT-20 | TWS119 | 0.04 | uM | LJP5 | 3 | M06 | 72 | hr | 1097 | 3893 | 3769 | 1.0328 | 1.0462 |
BT-20 | Vemurafenib | 0.04 | uM | LJP5 | 1 | C18 | 72 | hr | 1097 | 3746 | 3769 | 0.9938 | 0.9912 |
BT-20 | Vemurafenib | 0.04 | uM | LJP5 | 2 | C18 | 72 | hr | 1097 | 3479 | 3769 | 0.9229 | 0.8913 |
BT-20 | Vemurafenib | 0.04 | uM | LJP5 | 3 | C18 | 72 | hr | 1097 | 3814 | 3769 | 1.0118 | 1.0166 |
BT-20 | Withaferin A | 0.04 | uM | LJP5 | 1 | G18 | 72 | hr | 1097 | 4047 | 3769 | 1.0736 | 1.1038 |
BT-20 | Withaferin A | 0.04 | uM | LJP5 | 2 | G18 | 72 | hr | 1097 | 3915 | 3769 | 1.0386 | 1.0544 |
BT-20 | Withaferin A | 0.04 | uM | LJP5 | 3 | G18 | 72 | hr | 1097 | 4381 | 3769 | 1.1622 | 1.2288 |
BT-20 | Withaferin A | 0.04 | uM | LJP6 | 1 | G18 | 72 | hr | 1097 | 4101 | 3769 | 1.0879 | 1.1240 |