LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
Hs 578T XL147
0.04
uM
LJP5
 2
G12
 72
hr
 929 3243 3228 1.0046 1.0065
Hs 578T XL147
0.04
uM
LJP5
 3
G12
 72
hr
 929 3348 3228 1.0372 1.0522
Hs 578T Saracatinib
0.04
uM
LJP6
 1
D12
 72
hr
 929 3131 3228 0.9699 0.9578
Hs 578T Saracatinib
0.04
uM
LJP6
 2
D12
 72
hr
 929 3142 3228 0.9733 0.9626
Hs 578T Saracatinib
0.04
uM
LJP6
 3
D12
 72
hr
 929 3227 3228 0.9997 0.9995
Hs 578T Selumetinib
0.04
uM
LJP6
 1
M12
 72
hr
 929 1994 3228 0.6177 0.4632
Hs 578T Selumetinib
0.04
uM
LJP6
 2
M12
 72
hr
 929 2080 3228 0.6444 0.5006
Hs 578T Selumetinib
0.04
uM
LJP6
 3
M12
 72
hr
 929 1980 3228 0.6134 0.4571
Hs 578T Sirolimus
0.04
uM
LJP6
 1
L18
 72
hr
 929 2061 3228 0.6385 0.4923
Hs 578T Sirolimus
0.04
uM
LJP6
 2
L18
 72
hr
 929 2296 3228 0.7113 0.5946
Hs 578T Sirolimus
0.04
uM
LJP6
 3
L18
 72
hr
 929 2329 3228 0.7215 0.6089
Hs 578T Sorafenib
0.04
uM
LJP6
 1
B12
 72
hr
 929 3696 3228 1.1450 1.2036
Hs 578T Sorafenib
0.04
uM
LJP6
 2
B12
 72
hr
 929 3841 3228 1.1899 1.2666
Hs 578T Sorafenib
0.04
uM
LJP6
 3
B12
 72
hr
 929 3813 3228 1.1812 1.2545
Hs 578T SU11274
0.04
uM
LJP5
 1
J12
 72
hr
 929 3317 3228 1.0276 1.0387
Hs 578T SU11274
0.04
uM
LJP5
 2
J12
 72
hr
 929 3296 3228 1.0210 1.0296
Hs 578T SU11274
0.04
uM
LJP5
 3
J12
 72
hr
 929 3388 3228 1.0495 1.0696
Hs 578T Fedratinib
0.04
uM
LJP5
 1
L06
 72
hr
 929 3125 3228 0.9681 0.9552
Hs 578T Fedratinib
0.04
uM
LJP5
 2
L06
 72
hr
 929 3422 3228 1.0601 1.0844
Hs 578T Fedratinib
0.04
uM
LJP5
 3
L06
 72
hr
 929 3409 3228 1.0561 1.0787
Hs 578T TGX221
0.04
uM
LJP5
 1
H24
 72
hr
 929 2871 3228 0.8894 0.8447
Hs 578T TGX221
0.04
uM
LJP5
 2
H24
 72
hr
 929 3057 3228 0.9470 0.9256
Hs 578T TGX221
0.04
uM
LJP5
 3
H24
 72
hr
 929 3135 3228 0.9712 0.9595
Hs 578T Torin1
0.04
uM
LJP6
 1
O18
 72
hr
 929 1453 3228 0.4501 0.2278
Hs 578T Torin1
0.04
uM
LJP6
 2
O18
 72
hr
 929 1448 3228 0.4486 0.2257