LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
Hs 578T Torin1
0.04
uM
LJP6
 3
O18
 72
hr
 929 1388 3228 0.4300 0.1996
Hs 578T Torin2
0.04
uM
LJP5
 1
I24
 72
hr
 929 1328 3228 0.4114 0.1735
Hs 578T Torin2
0.04
uM
LJP5
 2
I24
 72
hr
 929 1442 3228 0.4467 0.2231
Hs 578T Torin2
0.04
uM
LJP5
 3
I24
 72
hr
 929 1440 3228 0.4461 0.2222
Hs 578T Tozasertib
0.04
uM
LJP5
 1
B18
 72
hr
 929 1365 3228 0.4229 0.1896
Hs 578T Tozasertib
0.04
uM
LJP5
 2
B18
 72
hr
 929 1375 3228 0.4260 0.1939
Hs 578T Tozasertib
0.04
uM
LJP5
 3
B18
 72
hr
 929 1457 3228 0.4514 0.2296
Hs 578T Trametinib
0.04
uM
LJP5
 1
P24
 72
hr
 929 1519 3228 0.4706 0.2566
Hs 578T Trametinib
0.04
uM
LJP5
 2
P24
 72
hr
 929 1472 3228 0.4560 0.2361
Hs 578T Trametinib
0.04
uM
LJP5
 3
P24
 72
hr
 929 1586 3228 0.4913 0.2857
Hs 578T TWS119
0.04
uM
LJP5
 1
M06
 72
hr
 929 3212 3228 0.9950 0.9930
Hs 578T TWS119
0.04
uM
LJP5
 2
M06
 72
hr
 929 3264 3228 1.0111 1.0156
Hs 578T TWS119
0.04
uM
LJP5
 3
M06
 72
hr
 929 3427 3228 1.0616 1.0865
Hs 578T Vemurafenib
0.04
uM
LJP5
 1
C18
 72
hr
 929 3283 3228 1.0170 1.0239
Hs 578T Vemurafenib
0.04
uM
LJP5
 2
C18
 72
hr
 929 3295 3228 1.0207 1.0291
Hs 578T Vemurafenib
0.04
uM
LJP5
 3
C18
 72
hr
 929 3373 3228 1.0449 1.0630
Hs 578T Withaferin A
0.04
uM
LJP5
 1
G18
 72
hr
 929 3186 3228 0.9870 0.9817
Hs 578T Withaferin A
0.04
uM
LJP5
 2
G18
 72
hr
 929 3239 3228 1.0034 1.0048
Hs 578T Withaferin A
0.04
uM
LJP5
 3
G18
 72
hr
 929 3256 3228 1.0087 1.0122
Hs 578T Withaferin A
0.04
uM
LJP6
 1
G18
 72
hr
 929 3266 3228 1.0118 1.0165
Hs 578T Withaferin A
0.04
uM
LJP6
 2
G18
 72
hr
 929 3181 3228 0.9854 0.9795
Hs 578T Withaferin A
0.04
uM
LJP6
 3
G18
 72
hr
 929 3257 3228 1.0090 1.0126
Hs 578T WYE-125132
0.04
uM
LJP6
 1
L12
 72
hr
 929 1385 3228 0.4291 0.1983
Hs 578T WYE-125132
0.04
uM
LJP6
 2
L12
 72
hr
 929 1398 3228 0.4331 0.2039
Hs 578T WYE-125132
0.04
uM
LJP6
 3
L12
 72
hr
 929 1485 3228 0.4600 0.2418