LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
Hs 578T Lapatinib
0.12
uM
LJP6
 3
M23
 72
hr
 929 3133 3228 0.9706 0.9587
Hs 578T LDN-193189
0.12
uM
LJP5
 1
G05
 72
hr
 929 2919 3228 0.9043 0.8656
Hs 578T LDN-193189
0.12
uM
LJP5
 2
G05
 72
hr
 929 3081 3228 0.9544 0.9360
Hs 578T LDN-193189
0.12
uM
LJP5
 3
G05
 72
hr
 929 3051 3228 0.9452 0.9230
Hs 578T Linifanib
0.12
uM
LJP6
 1
J11
 72
hr
 929 3148 3228 0.9752 0.9652
Hs 578T Linifanib
0.12
uM
LJP6
 2
J11
 72
hr
 929 3087 3228 0.9563 0.9386
Hs 578T Linifanib
0.12
uM
LJP6
 3
J11
 72
hr
 929 3129 3228 0.9693 0.9569
Hs 578T Linsitinib
0.12
uM
LJP5
 1
O23
 72
hr
 929 3116 3228 0.9653 0.9513
Hs 578T Linsitinib
0.12
uM
LJP5
 2
O23
 72
hr
 929 3185 3228 0.9867 0.9813
Hs 578T Linsitinib
0.12
uM
LJP5
 3
O23
 72
hr
 929 3110 3228 0.9634 0.9486
Hs 578T Mitoxantrone
0.12
uM
LJP5
 1
C23
 72
hr
 929 1055 3228 0.3268 0.0547
Hs 578T Mitoxantrone
0.12
uM
LJP5
 2
C23
 72
hr
 929 899 3228 0.2785 -0.0132
Hs 578T Mitoxantrone
0.12
uM
LJP5
 3
C23
 72
hr
 929 1097 3228 0.3398 0.0730
Hs 578T Mitoxantrone
0.12
uM
LJP6
 1
C23
 72
hr
 929 950 3228 0.2943 0.0090
Hs 578T Mitoxantrone
0.12
uM
LJP6
 2
C23
 72
hr
 929 912 3228 0.2825 -0.0075
Hs 578T Mitoxantrone
0.12
uM
LJP6
 3
C23
 72
hr
 929 962 3228 0.2980 0.0142
Hs 578T MK2206
0.12
uM
LJP6
 1
F05
 72
hr
 929 2566 3228 0.7949 0.7120
Hs 578T MK2206
0.12
uM
LJP6
 2
F05
 72
hr
 929 2611 3228 0.8088 0.7316
Hs 578T MK2206
0.12
uM
LJP6
 3
F05
 72
hr
 929 2748 3228 0.8513 0.7912
Hs 578T Neratinib
0.12
uM
LJP5
 1
A17
 72
hr
 929 2658 3228 0.8234 0.7520
Hs 578T Neratinib
0.12
uM
LJP5
 2
A17
 72
hr
 929 2780 3228 0.8612 0.8051
Hs 578T Neratinib
0.12
uM
LJP5
 3
A17
 72
hr
 929 2682 3228 0.8308 0.7625
Hs 578T Nilotinib
0.12
uM
LJP5
 1
N17
 72
hr
 929 3580 3228 1.1090 1.1531
Hs 578T Nilotinib
0.12
uM
LJP5
 2
N17
 72
hr
 929 3709 3228 1.1490 1.2092
Hs 578T Nilotinib
0.12
uM
LJP5
 3
N17
 72
hr
 929 3733 3228 1.1564 1.2197