LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
Hs 578T JW-7-24-1
0.04
uM
LJP6
 1
B24
 72
hr
 929 3051 3228 0.9452 0.9230
Hs 578T JW-7-24-1
0.04
uM
LJP6
 2
B24
 72
hr
 929 2916 3228 0.9033 0.8643
Hs 578T JW-7-24-1
0.04
uM
LJP6
 3
B24
 72
hr
 929 3186 3228 0.9870 0.9817
Hs 578T Lapatinib
0.04
uM
LJP6
 1
M24
 72
hr
 929 3316 3228 1.0274 1.0385
Hs 578T Lapatinib
0.04
uM
LJP6
 2
M24
 72
hr
 929 3156 3228 0.9777 0.9687
Hs 578T Lapatinib
0.04
uM
LJP6
 3
M24
 72
hr
 929 3107 3228 0.9625 0.9473
Hs 578T LDN-193189
0.04
uM
LJP5
 1
G06
 72
hr
 929 3036 3228 0.9405 0.9165
Hs 578T LDN-193189
0.04
uM
LJP5
 2
G06
 72
hr
 929 3161 3228 0.9792 0.9708
Hs 578T LDN-193189
0.04
uM
LJP5
 3
G06
 72
hr
 929 3155 3228 0.9774 0.9682
Hs 578T Linifanib
0.04
uM
LJP6
 1
J12
 72
hr
 929 3132 3228 0.9702 0.9582
Hs 578T Linifanib
0.04
uM
LJP6
 2
J12
 72
hr
 929 3101 3228 0.9606 0.9447
Hs 578T Linifanib
0.04
uM
LJP6
 3
J12
 72
hr
 929 3271 3228 1.0133 1.0187
Hs 578T Linsitinib
0.04
uM
LJP5
 1
O24
 72
hr
 929 3134 3228 0.9709 0.9591
Hs 578T Linsitinib
0.04
uM
LJP5
 2
O24
 72
hr
 929 3183 3228 0.9860 0.9804
Hs 578T Linsitinib
0.04
uM
LJP5
 3
O24
 72
hr
 929 3206 3228 0.9932 0.9904
Hs 578T Mitoxantrone
0.04
uM
LJP5
 1
C24
 72
hr
 929 1327 3228 0.4111 0.1730
Hs 578T Mitoxantrone
0.04
uM
LJP5
 2
C24
 72
hr
 929 1192 3228 0.3693 0.1143
Hs 578T Mitoxantrone
0.04
uM
LJP5
 3
C24
 72
hr
 929 1358 3228 0.4207 0.1865
Hs 578T Mitoxantrone
0.04
uM
LJP6
 1
C24
 72
hr
 929 1270 3228 0.3934 0.1482
Hs 578T Mitoxantrone
0.04
uM
LJP6
 2
C24
 72
hr
 929 1335 3228 0.4136 0.1765
Hs 578T Mitoxantrone
0.04
uM
LJP6
 3
C24
 72
hr
 929 1382 3228 0.4281 0.1970
Hs 578T MK2206
0.04
uM
LJP6
 1
F06
 72
hr
 929 2903 3228 0.8993 0.8586
Hs 578T MK2206
0.04
uM
LJP6
 2
F06
 72
hr
 929 2893 3228 0.8962 0.8543
Hs 578T MK2206
0.04
uM
LJP6
 3
F06
 72
hr
 929 2985 3228 0.9247 0.8943
Hs 578T Neratinib
0.04
uM
LJP5
 1
A18
 72
hr
 929 2939 3228 0.9105 0.8743