LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
Hs 578T Neratinib
0.04
uM
LJP5
 2
A18
 72
hr
 929 2915 3228 0.9030 0.8638
Hs 578T Neratinib
0.04
uM
LJP5
 3
A18
 72
hr
 929 2907 3228 0.9005 0.8603
Hs 578T Nilotinib
0.04
uM
LJP5
 1
N18
 72
hr
 929 3569 3228 1.1056 1.1483
Hs 578T Nilotinib
0.04
uM
LJP5
 2
N18
 72
hr
 929 3713 3228 1.1502 1.2109
Hs 578T Nilotinib
0.04
uM
LJP5
 3
N18
 72
hr
 929 3616 3228 1.1202 1.1688
Hs 578T Nintedanib
0.04
uM
LJP6
 1
H06
 72
hr
 929 2938 3228 0.9101 0.8738
Hs 578T Nintedanib
0.04
uM
LJP6
 2
H06
 72
hr
 929 2897 3228 0.8974 0.8560
Hs 578T Nintedanib
0.04
uM
LJP6
 3
H06
 72
hr
 929 3008 3228 0.9318 0.9043
Hs 578T NU7441
0.04
uM
LJP5
 1
C12
 72
hr
 929 3242 3228 1.0043 1.0061
Hs 578T NU7441
0.04
uM
LJP5
 2
C12
 72
hr
 929 3188 3228 0.9876 0.9826
Hs 578T NU7441
0.04
uM
LJP5
 3
C12
 72
hr
 929 3151 3228 0.9761 0.9665
Hs 578T Dactolisib
0.04
uM
LJP5
 1
M18
 72
hr
 929 1572 3228 0.4870 0.2796
Hs 578T Dactolisib
0.04
uM
LJP5
 2
M18
 72
hr
 929 1491 3228 0.4619 0.2444
Hs 578T Dactolisib
0.04
uM
LJP5
 3
M18
 72
hr
 929 1625 3228 0.5034 0.3027
Hs 578T NVP-TAE684
0.04
uM
LJP6
 1
K18
 72
hr
 929 2873 3228 0.8900 0.8456
Hs 578T NVP-TAE684
0.04
uM
LJP6
 2
K18
 72
hr
 929 2850 3228 0.8829 0.8355
Hs 578T NVP-TAE684
0.04
uM
LJP6
 3
K18
 72
hr
 929 2910 3228 0.9015 0.8616
Hs 578T Palbociclib
0.04
uM
LJP6
 1
E18
 72
hr
 929 2318 3228 0.7181 0.6041
Hs 578T Palbociclib
0.04
uM
LJP6
 2
E18
 72
hr
 929 2338 3228 0.7243 0.6128
Hs 578T Palbociclib
0.04
uM
LJP6
 3
E18
 72
hr
 929 2283 3228 0.7072 0.5889
Hs 578T PD0325901
0.04
uM
LJP5
 1
C06
 72
hr
 929 1833 3228 0.5678 0.3931
Hs 578T PD0325901
0.04
uM
LJP5
 2
C06
 72
hr
 929 1810 3228 0.5607 0.3831
Hs 578T PD0325901
0.04
uM
LJP5
 3
C06
 72
hr
 929 1821 3228 0.5641 0.3879
Hs 578T PD0325901
0.04
uM
LJP6
 1
E06
 72
hr
 929 1813 3228 0.5616 0.3844
Hs 578T PD0325901
0.04
uM
LJP6
 2
E06
 72
hr
 929 1707 3228 0.5288 0.3383