LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 SU11274
10.0
uM
LJP5
 2
J07
 72
hr
 868 1289 3486 0.3697 0.1608
MDA-MB-231 SU11274
10.0
uM
LJP5
 3
J07
 72
hr
 868 1269 3486 0.3640 0.1531
MDA-MB-231 Fedratinib
10.0
uM
LJP5
 1
L01
 72
hr
 868 696 3486 0.1996 -0.0657
MDA-MB-231 Fedratinib
10.0
uM
LJP5
 2
L01
 72
hr
 868 563 3486 0.1615 -0.1165
MDA-MB-231 Fedratinib
10.0
uM
LJP5
 3
L01
 72
hr
 868 596 3486 0.1710 -0.1039
MDA-MB-231 TGX221
10.0
uM
LJP5
 1
H19
 72
hr
 868 2858 3486 0.8198 0.7600
MDA-MB-231 TGX221
10.0
uM
LJP5
 2
H19
 72
hr
 868 2993 3486 0.8585 0.8116
MDA-MB-231 TGX221
10.0
uM
LJP5
 3
H19
 72
hr
 868 2831 3486 0.8120 0.7497
MDA-MB-231 Torin1
10.0
uM
LJP6
 1
O13
 72
hr
 868 1032 3486 0.2960 0.0626
MDA-MB-231 Torin1
10.0
uM
LJP6
 2
O13
 72
hr
 868 1003 3486 0.2877 0.0515
MDA-MB-231 Torin1
10.0
uM
LJP6
 3
O13
 72
hr
 868 1017 3486 0.2917 0.0569
MDA-MB-231 Torin2
10.0
uM
LJP5
 1
I19
 72
hr
 868 789 3486 0.2263 -0.0302
MDA-MB-231 Torin2
10.0
uM
LJP5
 2
I19
 72
hr
 868 924 3486 0.2650 0.0213
MDA-MB-231 Torin2
10.0
uM
LJP5
 3
I19
 72
hr
 868 871 3486 0.2498 0.0011
MDA-MB-231 Tozasertib
10.0
uM
LJP5
 1
B13
 72
hr
 868 1345 3486 0.3858 0.1821
MDA-MB-231 Tozasertib
10.0
uM
LJP5
 2
B13
 72
hr
 868 1306 3486 0.3746 0.1672
MDA-MB-231 Tozasertib
10.0
uM
LJP5
 3
B13
 72
hr
 868 1397 3486 0.4007 0.2020
MDA-MB-231 Trametinib
10.0
uM
LJP5
 1
P19
 72
hr
 868 1273 3486 0.3651 0.1546
MDA-MB-231 Trametinib
10.0
uM
LJP5
 2
P19
 72
hr
 868 1404 3486 0.4027 0.2047
MDA-MB-231 Trametinib
10.0
uM
LJP5
 3
P19
 72
hr
 868 1241 3486 0.3560 0.1424
MDA-MB-231 TWS119
10.0
uM
LJP5
 1
M01
 72
hr
 868 808 3486 0.2318 -0.0230
MDA-MB-231 TWS119
10.0
uM
LJP5
 2
M01
 72
hr
 868 806 3486 0.2312 -0.0237
MDA-MB-231 TWS119
10.0
uM
LJP5
 3
M01
 72
hr
 868 986 3486 0.2828 0.0450
MDA-MB-231 Vemurafenib
10.0
uM
LJP5
 1
C13
 72
hr
 868 1743 3486 0.4999 0.3341
MDA-MB-231 Vemurafenib
10.0
uM
LJP5
 2
C13
 72
hr
 868 1866 3486 0.5352 0.3811