LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Vemurafenib
10.0
uM
LJP5
 3
C13
 72
hr
 868 1677 3486 0.4810 0.3089
MDA-MB-231 Withaferin A
10.0
uM
LJP5
 1
G13
 72
hr
 868 475 3486 0.1362 -0.1501
MDA-MB-231 Withaferin A
10.0
uM
LJP5
 2
G13
 72
hr
 868 528 3486 0.1515 -0.1299
MDA-MB-231 Withaferin A
10.0
uM
LJP5
 3
G13
 72
hr
 868 425 3486 0.1219 -0.1692
MDA-MB-231 Withaferin A
10.0
uM
LJP6
 1
G13
 72
hr
 868 590 3486 0.1692 -0.1062
MDA-MB-231 Withaferin A
10.0
uM
LJP6
 2
G13
 72
hr
 868 475 3486 0.1362 -0.1501
MDA-MB-231 Withaferin A
10.0
uM
LJP6
 3
G13
 72
hr
 868 532 3486 0.1526 -0.1284
MDA-MB-231 WYE-125132
10.0
uM
LJP6
 1
L07
 72
hr
 868 1270 3486 0.3643 0.1535
MDA-MB-231 WYE-125132
10.0
uM
LJP6
 2
L07
 72
hr
 868 1454 3486 0.4171 0.2238
MDA-MB-231 WYE-125132
10.0
uM
LJP6
 3
L07
 72
hr
 868 1435 3486 0.4116 0.2165
MDA-MB-231 WZ3105
10.0
uM
LJP5
 1
D19
 72
hr
 868 750 3486 0.2151 -0.0451
MDA-MB-231 WZ3105
10.0
uM
LJP5
 2
D19
 72
hr
 868 946 3486 0.2713 0.0297
MDA-MB-231 WZ3105
10.0
uM
LJP5
 3
D19
 72
hr
 868 818 3486 0.2346 -0.0191
MDA-MB-231 XMD11-50
10.0
uM
LJP6
 1
P07
 72
hr
 868 1122 3486 0.3218 0.0970
MDA-MB-231 XMD11-50
10.0
uM
LJP6
 2
P07
 72
hr
 868 1470 3486 0.4216 0.2299
MDA-MB-231 XMD11-50
10.0
uM
LJP6
 3
P07
 72
hr
 868 1327 3486 0.3806 0.1753
MDA-MB-231 Y39983
10.0
uM
LJP6
 1
P01
 72
hr
 868 545 3486 0.1563 -0.1234
MDA-MB-231 Y39983
10.0
uM
LJP6
 2
P01
 72
hr
 868 600 3486 0.1721 -0.1024
MDA-MB-231 Y39983
10.0
uM
LJP6
 3
P01
 72
hr
 868 574 3486 0.1646 -0.1123
MDA-MB-231 YM 201636
10.0
uM
LJP5
 1
N07
 72
hr
 868 1640 3486 0.4704 0.2948
MDA-MB-231 YM 201636
10.0
uM
LJP5
 2
N07
 72
hr
 868 1679 3486 0.4816 0.3097
MDA-MB-231 YM 201636
10.0
uM
LJP5
 3
N07
 72
hr
 868 1474 3486 0.4228 0.2314
MDA-MB-231 ZSTK474
10.0
uM
LJP6
 1
M13
 72
hr
 868 1859 3486 0.5332 0.3785
MDA-MB-231 ZSTK474
10.0
uM
LJP6
 2
M13
 72
hr
 868 2129 3486 0.6107 0.4816
MDA-MB-231 ZSTK474
10.0
uM
LJP6
 3
M13
 72
hr
 868 1858 3486 0.5329 0.3781