LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 GW843682X
3.33
uM
LJP6
 1
B14
 72
hr
 868 1095 3486 0.3141 0.0867
MDA-MB-231 GW843682X
3.33
uM
LJP6
 2
B14
 72
hr
 868 999 3486 0.2865 0.0500
MDA-MB-231 GW843682X
3.33
uM
LJP6
 3
B14
 72
hr
 868 995 3486 0.2854 0.0485
MDA-MB-231 HG-5-113-01
3.33
uM
LJP5
 1
B08
 72
hr
 868 1193 3486 0.3422 0.1241
MDA-MB-231 HG-5-113-01
3.33
uM
LJP5
 2
B08
 72
hr
 868 1237 3486 0.3548 0.1409
MDA-MB-231 HG-5-113-01
3.33
uM
LJP5
 3
B08
 72
hr
 868 1107 3486 0.3175 0.0912
MDA-MB-231 HG-5-88-01
3.33
uM
LJP6
 1
A20
 72
hr
 868 2252 3486 0.6459 0.5286
MDA-MB-231 HG-5-88-01
3.33
uM
LJP6
 2
A20
 72
hr
 868 2125 3486 0.6095 0.4800
MDA-MB-231 HG-5-88-01
3.33
uM
LJP6
 3
A20
 72
hr
 868 2237 3486 0.6416 0.5228
MDA-MB-231 Imatinib
3.33
uM
LJP6
 1
N14
 72
hr
 868 3559 3486 1.0208 1.0277
MDA-MB-231 Imatinib
3.33
uM
LJP6
 2
N14
 72
hr
 868 3823 3486 1.0965 1.1286
MDA-MB-231 Imatinib
3.33
uM
LJP6
 3
N14
 72
hr
 868 3710 3486 1.0641 1.0854
MDA-MB-231 JNK-9L
3.33
uM
LJP6
 1
K20
 72
hr
 868 815 3486 0.2338 -0.0203
MDA-MB-231 JNK-9L
3.33
uM
LJP6
 2
K20
 72
hr
 868 842 3486 0.2415 -0.0100
MDA-MB-231 JNK-9L
3.33
uM
LJP6
 3
K20
 72
hr
 868 895 3486 0.2567 0.0103
MDA-MB-231 JW-7-24-1
3.33
uM
LJP6
 1
B20
 72
hr
 868 1893 3486 0.5430 0.3914
MDA-MB-231 JW-7-24-1
3.33
uM
LJP6
 2
B20
 72
hr
 868 1917 3486 0.5499 0.4006
MDA-MB-231 JW-7-24-1
3.33
uM
LJP6
 3
B20
 72
hr
 868 1833 3486 0.5258 0.3685
MDA-MB-231 Lapatinib
3.33
uM
LJP6
 1
M20
 72
hr
 868 3125 3486 0.8963 0.8620
MDA-MB-231 Lapatinib
3.33
uM
LJP6
 2
M20
 72
hr
 868 3515 3486 1.0082 1.0109
MDA-MB-231 Lapatinib
3.33
uM
LJP6
 3
M20
 72
hr
 868 3481 3486 0.9985 0.9979
MDA-MB-231 LDN-193189
3.33
uM
LJP5
 1
G02
 72
hr
 868 849 3486 0.2435 -0.0073
MDA-MB-231 LDN-193189
3.33
uM
LJP5
 2
G02
 72
hr
 868 1081 3486 0.3101 0.0813
MDA-MB-231 LDN-193189
3.33
uM
LJP5
 3
G02
 72
hr
 868 1314 3486 0.3769 0.1703
MDA-MB-231 Linifanib
3.33
uM
LJP6
 1
J08
 72
hr
 868 3686 3486 1.0573 1.0762