LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Pictilisib
3.33
uM
LJP6
 3
D20
 72
hr
 868 2392 3486 0.6861 0.5820
MDA-MB-231 Gefitinib
3.33
uM
LJP6
 1
N08
 72
hr
 868 3614 3486 1.0366 1.0487
MDA-MB-231 Gefitinib
3.33
uM
LJP6
 2
N08
 72
hr
 868 3948 3486 1.1324 1.1763
MDA-MB-231 Gefitinib
3.33
uM
LJP6
 3
N08
 72
hr
 868 3982 3486 1.1422 1.1893
MDA-MB-231 Geldanamycin
3.33
uM
LJP5
 1
O02
 72
hr
 868 926 3486 0.2656 0.0221
MDA-MB-231 Geldanamycin
3.33
uM
LJP5
 2
O02
 72
hr
 868 762 3486 0.2186 -0.0405
MDA-MB-231 Geldanamycin
3.33
uM
LJP5
 3
O02
 72
hr
 868 890 3486 0.2553 0.0084
MDA-MB-231 Geldanamycin
3.33
uM
LJP6
 1
O02
 72
hr
 868 919 3486 0.2636 0.0194
MDA-MB-231 Geldanamycin
3.33
uM
LJP6
 2
O02
 72
hr
 868 854 3486 0.2450 -0.0054
MDA-MB-231 Geldanamycin
3.33
uM
LJP6
 3
O02
 72
hr
 868 1120 3486 0.3213 0.0962
MDA-MB-231 GSK1059615
3.33
uM
LJP5
 1
E02
 72
hr
 868 686 3486 0.1968 -0.0696
MDA-MB-231 GSK1059615
3.33
uM
LJP5
 2
E02
 72
hr
 868 764 3486 0.2191 -0.0398
MDA-MB-231 GSK1059615
3.33
uM
LJP5
 3
E02
 72
hr
 868 893 3486 0.2561 0.0095
MDA-MB-231 GSK1059615
3.33
uM
LJP6
 1
C02
 72
hr
 868 1019 3486 0.2923 0.0576
MDA-MB-231 GSK1059615
3.33
uM
LJP6
 2
C02
 72
hr
 868 1173 3486 0.3365 0.1164
MDA-MB-231 GSK1059615
3.33
uM
LJP6
 3
C02
 72
hr
 868 1344 3486 0.3855 0.1818
MDA-MB-231 GSK1904529A
3.33
uM
LJP6
 1
H20
 72
hr
 868 3076 3486 0.8823 0.8433
MDA-MB-231 GSK1904529A
3.33
uM
LJP6
 2
H20
 72
hr
 868 3393 3486 0.9732 0.9643
MDA-MB-231 GSK1904529A
3.33
uM
LJP6
 3
H20
 72
hr
 868 3720 3486 1.0670 1.0892
MDA-MB-231 Omipalisib
3.33
uM
LJP6
 1
N02
 72
hr
 868 887 3486 0.2544 0.0072
MDA-MB-231 Omipalisib
3.33
uM
LJP6
 2
N02
 72
hr
 868 1203 3486 0.3451 0.1279
MDA-MB-231 Omipalisib
3.33
uM
LJP6
 3
N02
 72
hr
 868 1000 3486 0.2868 0.0504
MDA-MB-231 GSK 690693
3.33
uM
LJP5
 1
F20
 72
hr
 868 3217 3486 0.9227 0.8971
MDA-MB-231 GSK 690693
3.33
uM
LJP5
 2
F20
 72
hr
 868 3514 3486 1.0079 1.0105
MDA-MB-231 GSK 690693
3.33
uM
LJP5
 3
F20
 72
hr
 868 3648 3486 1.0464 1.0617