LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 JW-7-24-1
0.37
uM
LJP6
 1
B22
 72
hr
 868 2360 3486 0.6769 0.5698
MDA-MB-231 JW-7-24-1
0.37
uM
LJP6
 2
B22
 72
hr
 868 2556 3486 0.7331 0.6447
MDA-MB-231 JW-7-24-1
0.37
uM
LJP6
 3
B22
 72
hr
 868 2362 3486 0.6775 0.5706
MDA-MB-231 Lapatinib
0.37
uM
LJP6
 1
M22
 72
hr
 868 3353 3486 0.9617 0.9491
MDA-MB-231 Lapatinib
0.37
uM
LJP6
 2
M22
 72
hr
 868 3502 3486 1.0045 1.0060
MDA-MB-231 Lapatinib
0.37
uM
LJP6
 3
M22
 72
hr
 868 3200 3486 0.9179 0.8906
MDA-MB-231 LDN-193189
0.37
uM
LJP5
 1
G04
 72
hr
 868 3538 3486 1.0148 1.0197
MDA-MB-231 LDN-193189
0.37
uM
LJP5
 2
G04
 72
hr
 868 3641 3486 1.0443 1.0590
MDA-MB-231 LDN-193189
0.37
uM
LJP5
 3
G04
 72
hr
 868 3106 3486 0.8909 0.8547
MDA-MB-231 Linifanib
0.37
uM
LJP6
 1
J10
 72
hr
 868 3816 3486 1.0945 1.1259
MDA-MB-231 Linifanib
0.37
uM
LJP6
 2
J10
 72
hr
 868 3991 3486 1.1447 1.1927
MDA-MB-231 Linifanib
0.37
uM
LJP6
 3
J10
 72
hr
 868 4305 3486 1.2348 1.3126
MDA-MB-231 Linsitinib
0.37
uM
LJP5
 1
O22
 72
hr
 868 2628 3486 0.7538 0.6722
MDA-MB-231 Linsitinib
0.37
uM
LJP5
 2
O22
 72
hr
 868 2956 3486 0.8479 0.7974
MDA-MB-231 Linsitinib
0.37
uM
LJP5
 3
O22
 72
hr
 868 3041 3486 0.8723 0.8299
MDA-MB-231 Mitoxantrone
0.37
uM
LJP5
 1
C22
 72
hr
 868 748 3486 0.2146 -0.0459
MDA-MB-231 Mitoxantrone
0.37
uM
LJP5
 2
C22
 72
hr
 868 782 3486 0.2243 -0.0329
MDA-MB-231 Mitoxantrone
0.37
uM
LJP5
 3
C22
 72
hr
 868 902 3486 0.2587 0.0129
MDA-MB-231 Mitoxantrone
0.37
uM
LJP6
 1
C22
 72
hr
 868 880 3486 0.2524 0.0045
MDA-MB-231 Mitoxantrone
0.37
uM
LJP6
 2
C22
 72
hr
 868 801 3486 0.2298 -0.0256
MDA-MB-231 Mitoxantrone
0.37
uM
LJP6
 3
C22
 72
hr
 868 802 3486 0.2300 -0.0253
MDA-MB-231 MK2206
0.37
uM
LJP6
 1
F04
 72
hr
 868 2806 3486 0.8048 0.7401
MDA-MB-231 MK2206
0.37
uM
LJP6
 2
F04
 72
hr
 868 2720 3486 0.7802 0.7073
MDA-MB-231 MK2206
0.37
uM
LJP6
 3
F04
 72
hr
 868 2761 3486 0.7919 0.7230
MDA-MB-231 Neratinib
0.37
uM
LJP5
 1
A16
 72
hr
 868 2225 3486 0.6382 0.5182