LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Tozasertib | 10.0 | uM | LJP5 | 2 | B13 | 72 | hr | 513 | 770 | 10401 | 0.0740 | 0.0260 |
| MCF 10A | Tozasertib | 10.0 | uM | LJP5 | 3 | B13 | 72 | hr | 513 | 962 | 10401 | 0.0925 | 0.0454 |
| MCF 10A | Trametinib | 10.0 | uM | LJP5 | 1 | P19 | 72 | hr | 513 | 1075 | 10401 | 0.1034 | 0.0568 |
| MCF 10A | Trametinib | 10.0 | uM | LJP5 | 2 | P19 | 72 | hr | 513 | 988 | 10401 | 0.0950 | 0.0480 |
| MCF 10A | Trametinib | 10.0 | uM | LJP5 | 3 | P19 | 72 | hr | 513 | 999 | 10401 | 0.0960 | 0.0491 |
| MCF 10A | TWS119 | 10.0 | uM | LJP5 | 1 | M01 | 72 | hr | 513 | 399 | 10401 | 0.0384 | -0.0116 |
| MCF 10A | TWS119 | 10.0 | uM | LJP5 | 2 | M01 | 72 | hr | 513 | 373 | 10401 | 0.0359 | -0.0142 |
| MCF 10A | TWS119 | 10.0 | uM | LJP5 | 3 | M01 | 72 | hr | 513 | 385 | 10401 | 0.0370 | -0.0130 |
| MCF 10A | Vemurafenib | 10.0 | uM | LJP5 | 1 | C13 | 72 | hr | 513 | 1772 | 10401 | 0.1704 | 0.1273 |
| MCF 10A | Vemurafenib | 10.0 | uM | LJP5 | 2 | C13 | 72 | hr | 513 | 1862 | 10401 | 0.1790 | 0.1364 |
| MCF 10A | Vemurafenib | 10.0 | uM | LJP5 | 3 | C13 | 72 | hr | 513 | 2077 | 10401 | 0.1997 | 0.1581 |
| MCF 10A | Withaferin A | 10.0 | uM | LJP5 | 1 | G13 | 72 | hr | 513 | 248 | 10401 | 0.0238 | -0.0268 |
| MCF 10A | Withaferin A | 10.0 | uM | LJP5 | 2 | G13 | 72 | hr | 513 | 359 | 10401 | 0.0345 | -0.0156 |
| MCF 10A | Withaferin A | 10.0 | uM | LJP5 | 3 | G13 | 72 | hr | 513 | 358 | 10401 | 0.0344 | -0.0157 |
| MCF 10A | Withaferin A | 10.0 | uM | LJP6 | 1 | G13 | 72 | hr | 513 | 236 | 10401 | 0.0227 | -0.0281 |
| MCF 10A | Withaferin A | 10.0 | uM | LJP6 | 2 | G13 | 72 | hr | 513 | 301 | 10401 | 0.0289 | -0.0215 |
| MCF 10A | Withaferin A | 10.0 | uM | LJP6 | 3 | G13 | 72 | hr | 513 | 438 | 10401 | 0.0421 | -0.0076 |
| MCF 10A | WYE-125132 | 10.0 | uM | LJP6 | 1 | L07 | 72 | hr | 513 | 949 | 10401 | 0.0912 | 0.0441 |
| MCF 10A | WYE-125132 | 10.0 | uM | LJP6 | 2 | L07 | 72 | hr | 513 | 666 | 10401 | 0.0640 | 0.0154 |
| MCF 10A | WYE-125132 | 10.0 | uM | LJP6 | 3 | L07 | 72 | hr | 513 | 1031 | 10401 | 0.0991 | 0.0524 |
| MCF 10A | WZ3105 | 10.0 | uM | LJP5 | 1 | D19 | 72 | hr | 513 | 548 | 10401 | 0.0527 | 0.0035 |
| MCF 10A | WZ3105 | 10.0 | uM | LJP5 | 2 | D19 | 72 | hr | 513 | 468 | 10401 | 0.0450 | -0.0046 |
| MCF 10A | WZ3105 | 10.0 | uM | LJP5 | 3 | D19 | 72 | hr | 513 | 560 | 10401 | 0.0538 | 0.0047 |
| MCF 10A | XMD11-50 | 10.0 | uM | LJP6 | 1 | P07 | 72 | hr | 513 | 894 | 10401 | 0.0860 | 0.0385 |
| MCF 10A | XMD11-50 | 10.0 | uM | LJP6 | 2 | P07 | 72 | hr | 513 | 940 | 10401 | 0.0904 | 0.0431 |