LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MCF7 NU7441
0.04
uM
LJP5
 3
C12
 72
hr
 1235 4332 4156 1.0423 1.0602
MCF7 Dactolisib
0.04
uM
LJP5
 1
M18
 72
hr
 1235 1779 4156 0.4280 0.1861
MCF7 Dactolisib
0.04
uM
LJP5
 2
M18
 72
hr
 1235 2049 4156 0.4930 0.2786
MCF7 Dactolisib
0.04
uM
LJP5
 3
M18
 72
hr
 1235 1944 4156 0.4677 0.2426
MCF7 NVP-TAE684
0.04
uM
LJP6
 1
K18
 72
hr
 1235 2917 4156 0.7019 0.5757
MCF7 NVP-TAE684
0.04
uM
LJP6
 2
K18
 72
hr
 1235 2474 4156 0.5953 0.4241
MCF7 NVP-TAE684
0.04
uM
LJP6
 3
K18
 72
hr
 1235 2508 4156 0.6034 0.4357
MCF7 Palbociclib
0.04
uM
LJP6
 1
E18
 72
hr
 1235 2819 4156 0.6783 0.5422
MCF7 Palbociclib
0.04
uM
LJP6
 2
E18
 72
hr
 1235 2950 4156 0.7098 0.5870
MCF7 Palbociclib
0.04
uM
LJP6
 3
E18
 72
hr
 1235 3286 4156 0.7906 0.7021
MCF7 PD0325901
0.04
uM
LJP5
 1
C06
 72
hr
 1235 2870 4156 0.6905 0.5597
MCF7 PD0325901
0.04
uM
LJP5
 2
C06
 72
hr
 1235 2819 4156 0.6783 0.5422
MCF7 PD0325901
0.04
uM
LJP5
 3
C06
 72
hr
 1235 3189 4156 0.7673 0.6689
MCF7 PD0325901
0.04
uM
LJP6
 1
E06
 72
hr
 1235 2676 4156 0.6439 0.4932
MCF7 PD0325901
0.04
uM
LJP6
 2
E06
 72
hr
 1235 3107 4156 0.7476 0.6408
MCF7 PD0325901
0.04
uM
LJP6
 3
E06
 72
hr
 1235 3053 4156 0.7346 0.6223
MCF7 PD173074
0.04
uM
LJP6
 1
I12
 72
hr
 1235 4556 4156 1.0962 1.1369
MCF7 PD173074
0.04
uM
LJP6
 2
I12
 72
hr
 1235 4605 4156 1.1080 1.1537
MCF7 PD173074
0.04
uM
LJP6
 3
I12
 72
hr
 1235 4376 4156 1.0529 1.0753
MCF7 PD184352
0.04
uM
LJP5
 1
L12
 72
hr
 1235 3806 4156 0.9158 0.8801
MCF7 PD184352
0.04
uM
LJP5
 2
L12
 72
hr
 1235 4240 4156 1.0202 1.0287
MCF7 PD184352
0.04
uM
LJP5
 3
L12
 72
hr
 1235 4336 4156 1.0433 1.0616
MCF7 Pelitinib
0.04
uM
LJP5
 1
I18
 72
hr
 1235 4492 4156 1.0808 1.1150
MCF7 Pelitinib
0.04
uM
LJP5
 2
I18
 72
hr
 1235 4733 4156 1.1388 1.1975
MCF7 Pelitinib
0.04
uM
LJP5
 3
I18
 72
hr
 1235 5043 4156 1.2134 1.3036