LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | A443654 | 10.0 | uM | LJP6 | 1 | I19 | 72 | hr | 513 | 471 | 10401 | 0.0453 | -0.0043 |
| MCF 10A | A443654 | 10.0 | uM | LJP6 | 2 | I19 | 72 | hr | 513 | 344 | 10401 | 0.0331 | -0.0171 |
| MCF 10A | A443654 | 10.0 | uM | LJP6 | 3 | I19 | 72 | hr | 513 | 432 | 10401 | 0.0415 | -0.0082 |
| MCF 10A | OSI-027 | 10.0 | uM | LJP6 | 1 | E07 | 72 | hr | 513 | 922 | 10401 | 0.0886 | 0.0413 |
| MCF 10A | OSI-027 | 10.0 | uM | LJP6 | 2 | E07 | 72 | hr | 513 | 907 | 10401 | 0.0872 | 0.0398 |
| MCF 10A | OSI-027 | 10.0 | uM | LJP6 | 3 | E07 | 72 | hr | 513 | 685 | 10401 | 0.0659 | 0.0174 |
| MCF 10A | XMD11-85h | 10.0 | uM | LJP6 | 1 | P19 | 72 | hr | 513 | 5858 | 10401 | 0.5632 | 0.5405 |
| MCF 10A | XMD11-85h | 10.0 | uM | LJP6 | 2 | P19 | 72 | hr | 513 | 4659 | 10401 | 0.4479 | 0.4193 |
| MCF 10A | XMD11-85h | 10.0 | uM | LJP6 | 3 | P19 | 72 | hr | 513 | 5333 | 10401 | 0.5127 | 0.4874 |
| MCF 10A | HG-6-64-01 | 10.0 | uM | LJP6 | 1 | M01 | 72 | hr | 513 | 204 | 10401 | 0.0196 | -0.0313 |
| MCF 10A | HG-6-64-01 | 10.0 | uM | LJP6 | 2 | M01 | 72 | hr | 513 | 241 | 10401 | 0.0232 | -0.0275 |
| MCF 10A | HG-6-64-01 | 10.0 | uM | LJP6 | 3 | M01 | 72 | hr | 513 | 293 | 10401 | 0.0282 | -0.0223 |
| MCF 10A | WH-4-025 | 10.0 | uM | LJP5 | 1 | O07 | 72 | hr | 513 | 787 | 10401 | 0.0757 | 0.0277 |
| MCF 10A | WH-4-025 | 10.0 | uM | LJP5 | 2 | O07 | 72 | hr | 513 | 957 | 10401 | 0.0920 | 0.0449 |
| MCF 10A | WH-4-025 | 10.0 | uM | LJP5 | 3 | O07 | 72 | hr | 513 | 904 | 10401 | 0.0869 | 0.0395 |
| MCF 10A | WZ-4-145 | 10.0 | uM | LJP6 | 1 | J19 | 72 | hr | 513 | 536 | 10401 | 0.0515 | 0.0023 |
| MCF 10A | WZ-4-145 | 10.0 | uM | LJP6 | 2 | J19 | 72 | hr | 513 | 461 | 10401 | 0.0443 | -0.0053 |
| MCF 10A | WZ-4-145 | 10.0 | uM | LJP6 | 3 | J19 | 72 | hr | 513 | 452 | 10401 | 0.0435 | -0.0062 |
| MCF 10A | XMD16-144 | 10.0 | uM | LJP5 | 1 | M07 | 72 | hr | 513 | 562 | 10401 | 0.0540 | 0.0049 |
| MCF 10A | XMD16-144 | 10.0 | uM | LJP5 | 2 | M07 | 72 | hr | 513 | 791 | 10401 | 0.0760 | 0.0281 |
| MCF 10A | XMD16-144 | 10.0 | uM | LJP5 | 3 | M07 | 72 | hr | 513 | 594 | 10401 | 0.0571 | 0.0082 |
| MCF 10A | Brivanib | 10.0 | uM | LJP5 | 1 | P13 | 72 | hr | 513 | 1462 | 10401 | 0.1406 | 0.0959 |
| MCF 10A | Brivanib | 10.0 | uM | LJP5 | 2 | P13 | 72 | hr | 513 | 1444 | 10401 | 0.1388 | 0.0941 |
| MCF 10A | Brivanib | 10.0 | uM | LJP5 | 3 | P13 | 72 | hr | 513 | 1533 | 10401 | 0.1474 | 0.1031 |
| MCF 10A | Buparlisib | 10.0 | uM | LJP5 | 1 | H01 | 72 | hr | 513 | 344 | 10401 | 0.0331 | -0.0171 |