LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MCF 10A XMD11-50
10.0
uM
LJP6
 3
P07
 72
hr
 513 960 10401 0.0923 0.0452
MCF 10A Y39983
10.0
uM
LJP6
 1
P01
 72
hr
 513 1118 10401 0.1075 0.0612
MCF 10A Y39983
10.0
uM
LJP6
 2
P01
 72
hr
 513 1054 10401 0.1013 0.0547
MCF 10A Y39983
10.0
uM
LJP6
 3
P01
 72
hr
 513 1228 10401 0.1181 0.0723
MCF 10A YM 201636
10.0
uM
LJP5
 1
N07
 72
hr
 513 1304 10401 0.1254 0.0800
MCF 10A YM 201636
10.0
uM
LJP5
 2
N07
 72
hr
 513 1526 10401 0.1467 0.1024
MCF 10A YM 201636
10.0
uM
LJP5
 3
N07
 72
hr
 513 1338 10401 0.1286 0.0834
MCF 10A ZSTK474
10.0
uM
LJP6
 1
M13
 72
hr
 513 1383 10401 0.1330 0.0880
MCF 10A ZSTK474
10.0
uM
LJP6
 2
M13
 72
hr
 513 1425 10401 0.1370 0.0922
MCF 10A ZSTK474
10.0
uM
LJP6
 3
M13
 72
hr
 513 1068 10401 0.1027 0.0561
MCF7 Afatinib
0.04
uM
LJP6
 1
G24
 72
hr
 1235 2953 4156 0.7105 0.5881
MCF7 Afatinib
0.04
uM
LJP6
 2
G24
 72
hr
 1235 2855 4156 0.6869 0.5545
MCF7 Afatinib
0.04
uM
LJP6
 3
G24
 72
hr
 1235 2684 4156 0.6458 0.4960
MCF7 Sigma A6730
0.04
uM
LJP5
 1
B24
 72
hr
 1235 2961 4156 0.7124 0.5908
MCF7 Sigma A6730
0.04
uM
LJP5
 2
B24
 72
hr
 1235 3319 4156 0.7986 0.7134
MCF7 Sigma A6730
0.04
uM
LJP5
 3
B24
 72
hr
 1235 3712 4156 0.8931 0.8479
MCF7 Alvocidib
0.04
uM
LJP6
 1
A18
 72
hr
 1235 1106 4156 0.2661 -0.0443
MCF7 Alvocidib
0.04
uM
LJP6
 2
A18
 72
hr
 1235 1183 4156 0.2846 -0.0179
MCF7 Alvocidib
0.04
uM
LJP6
 3
A18
 72
hr
 1235 1089 4156 0.2620 -0.0501
MCF7 AT-7519
0.04
uM
LJP6
 1
K06
 72
hr
 1235 3316 4156 0.7979 0.7124
MCF7 AT-7519
0.04
uM
LJP6
 2
K06
 72
hr
 1235 3573 4156 0.8597 0.8003
MCF7 AT-7519
0.04
uM
LJP6
 3
K06
 72
hr
 1235 3793 4156 0.9126 0.8757
MCF7 AZD 5438
0.04
uM
LJP6
 1
J06
 72
hr
 1235 3524 4156 0.8479 0.7836
MCF7 AZD 5438
0.04
uM
LJP6
 2
J06
 72
hr
 1235 3373 4156 0.8116 0.7319
MCF7 AZD 5438
0.04
uM
LJP6
 3
J06
 72
hr
 1235 3812 4156 0.9172 0.8822