LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | Sirolimus | 1.11 | uM | LJP6 | 3 | L15 | 72 | hr | 1657 | 3474 | 5505 | 0.6310 | 0.4720 |
| BT-20 | Sorafenib | 1.11 | uM | LJP6 | 1 | B09 | 72 | hr | 1657 | 4637 | 5505 | 0.8422 | 0.7743 |
| BT-20 | Sorafenib | 1.11 | uM | LJP6 | 2 | B09 | 72 | hr | 1657 | 4689 | 5505 | 0.8517 | 0.7878 |
| BT-20 | Sorafenib | 1.11 | uM | LJP6 | 3 | B09 | 72 | hr | 1657 | 4845 | 5505 | 0.8800 | 0.8283 |
| BT-20 | SU11274 | 1.11 | uM | LJP5 | 1 | J09 | 72 | hr | 1657 | 4941 | 5505 | 0.8974 | 0.8533 |
| BT-20 | SU11274 | 1.11 | uM | LJP5 | 2 | J09 | 72 | hr | 1657 | 5489 | 5505 | 0.9970 | 0.9957 |
| BT-20 | SU11274 | 1.11 | uM | LJP5 | 3 | J09 | 72 | hr | 1657 | 5433 | 5505 | 0.9868 | 0.9811 |
| BT-20 | Fedratinib | 1.11 | uM | LJP5 | 1 | L03 | 72 | hr | 1657 | 4693 | 5505 | 0.8524 | 0.7888 |
| BT-20 | Fedratinib | 1.11 | uM | LJP5 | 2 | L03 | 72 | hr | 1657 | 4975 | 5505 | 0.9036 | 0.8621 |
| BT-20 | Fedratinib | 1.11 | uM | LJP5 | 3 | L03 | 72 | hr | 1657 | 4655 | 5505 | 0.8455 | 0.7789 |
| BT-20 | TGX221 | 1.11 | uM | LJP5 | 1 | H21 | 72 | hr | 1657 | 5535 | 5505 | 1.0053 | 1.0076 |
| BT-20 | TGX221 | 1.11 | uM | LJP5 | 2 | H21 | 72 | hr | 1657 | 5412 | 5505 | 0.9830 | 0.9757 |
| BT-20 | TGX221 | 1.11 | uM | LJP5 | 3 | H21 | 72 | hr | 1657 | 5400 | 5505 | 0.9808 | 0.9725 |
| BT-20 | Torin1 | 1.11 | uM | LJP6 | 1 | O15 | 72 | hr | 1657 | 1287 | 5505 | 0.2338 | -0.0963 |
| BT-20 | Torin1 | 1.11 | uM | LJP6 | 2 | O15 | 72 | hr | 1657 | 1386 | 5505 | 0.2517 | -0.0706 |
| BT-20 | Torin1 | 1.11 | uM | LJP6 | 3 | O15 | 72 | hr | 1657 | 1680 | 5505 | 0.3051 | 0.0058 |
| BT-20 | Torin2 | 1.11 | uM | LJP5 | 1 | I21 | 72 | hr | 1657 | 1319 | 5505 | 0.2396 | -0.0880 |
| BT-20 | Torin2 | 1.11 | uM | LJP5 | 2 | I21 | 72 | hr | 1657 | 1191 | 5505 | 0.2163 | -0.1213 |
| BT-20 | Torin2 | 1.11 | uM | LJP5 | 3 | I21 | 72 | hr | 1657 | 1425 | 5505 | 0.2588 | -0.0605 |
| BT-20 | Tozasertib | 1.11 | uM | LJP5 | 1 | B15 | 72 | hr | 1657 | 1702 | 5505 | 0.3091 | 0.0115 |
| BT-20 | Tozasertib | 1.11 | uM | LJP5 | 2 | B15 | 72 | hr | 1657 | 1785 | 5505 | 0.3242 | 0.0331 |
| BT-20 | Tozasertib | 1.11 | uM | LJP5 | 3 | B15 | 72 | hr | 1657 | 1709 | 5505 | 0.3104 | 0.0133 |
| BT-20 | Trametinib | 1.11 | uM | LJP5 | 1 | P21 | 72 | hr | 1657 | 3977 | 5505 | 0.7224 | 0.6027 |
| BT-20 | Trametinib | 1.11 | uM | LJP5 | 2 | P21 | 72 | hr | 1657 | 4480 | 5505 | 0.8137 | 0.7335 |
| BT-20 | Trametinib | 1.11 | uM | LJP5 | 3 | P21 | 72 | hr | 1657 | 4419 | 5505 | 0.8026 | 0.7176 |