LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | QL-XII-47 | 1.11 | uM | LJP6 | 2 | O21 | 72 | hr | 1657 | 1697 | 5505 | 0.3082 | 0.0102 |
| BT-20 | QL-XII-47 | 1.11 | uM | LJP6 | 3 | O21 | 72 | hr | 1657 | 1628 | 5505 | 0.2957 | -0.0077 |
| BT-20 | Radicicol | 1.11 | uM | LJP5 | 1 | K09 | 72 | hr | 1657 | 1984 | 5505 | 0.3604 | 0.0848 |
| BT-20 | Radicicol | 1.11 | uM | LJP5 | 2 | K09 | 72 | hr | 1657 | 1878 | 5505 | 0.3411 | 0.0572 |
| BT-20 | Radicicol | 1.11 | uM | LJP5 | 3 | K09 | 72 | hr | 1657 | 1814 | 5505 | 0.3295 | 0.0406 |
| BT-20 | Radicicol | 1.11 | uM | LJP6 | 1 | K09 | 72 | hr | 1657 | 2049 | 5505 | 0.3722 | 0.1017 |
| BT-20 | Radicicol | 1.11 | uM | LJP6 | 2 | K09 | 72 | hr | 1657 | 1964 | 5505 | 0.3567 | 0.0796 |
| BT-20 | Radicicol | 1.11 | uM | LJP6 | 3 | K09 | 72 | hr | 1657 | 1795 | 5505 | 0.3260 | 0.0357 |
| BT-20 | Seliciclib | 1.11 | uM | LJP5 | 1 | J03 | 72 | hr | 1657 | 4597 | 5505 | 0.8350 | 0.7639 |
| BT-20 | Seliciclib | 1.11 | uM | LJP5 | 2 | J03 | 72 | hr | 1657 | 4956 | 5505 | 0.9002 | 0.8572 |
| BT-20 | Seliciclib | 1.11 | uM | LJP5 | 3 | J03 | 72 | hr | 1657 | 4738 | 5505 | 0.8606 | 0.8005 |
| BT-20 | Ruxolitinib | 1.11 | uM | LJP5 | 1 | O15 | 72 | hr | 1657 | 4914 | 5505 | 0.8925 | 0.8462 |
| BT-20 | Ruxolitinib | 1.11 | uM | LJP5 | 2 | O15 | 72 | hr | 1657 | 5210 | 5505 | 0.9463 | 0.9232 |
| BT-20 | Ruxolitinib | 1.11 | uM | LJP5 | 3 | O15 | 72 | hr | 1657 | 5019 | 5505 | 0.9116 | 0.8735 |
| BT-20 | XL147 | 1.11 | uM | LJP5 | 1 | G09 | 72 | hr | 1657 | 5418 | 5505 | 0.9841 | 0.9772 |
| BT-20 | XL147 | 1.11 | uM | LJP5 | 2 | G09 | 72 | hr | 1657 | 5178 | 5505 | 0.9405 | 0.9149 |
| BT-20 | XL147 | 1.11 | uM | LJP5 | 3 | G09 | 72 | hr | 1657 | 5199 | 5505 | 0.9443 | 0.9203 |
| BT-20 | Saracatinib | 1.11 | uM | LJP6 | 1 | D09 | 72 | hr | 1657 | 3918 | 5505 | 0.7116 | 0.5874 |
| BT-20 | Saracatinib | 1.11 | uM | LJP6 | 2 | D09 | 72 | hr | 1657 | 4215 | 5505 | 0.7656 | 0.6646 |
| BT-20 | Saracatinib | 1.11 | uM | LJP6 | 3 | D09 | 72 | hr | 1657 | 4905 | 5505 | 0.8909 | 0.8439 |
| BT-20 | Selumetinib | 1.11 | uM | LJP6 | 1 | M09 | 72 | hr | 1657 | 5818 | 5505 | 1.0567 | 1.0812 |
| BT-20 | Selumetinib | 1.11 | uM | LJP6 | 2 | M09 | 72 | hr | 1657 | 5785 | 5505 | 1.0507 | 1.0726 |
| BT-20 | Selumetinib | 1.11 | uM | LJP6 | 3 | M09 | 72 | hr | 1657 | 5599 | 5505 | 1.0170 | 1.0243 |
| BT-20 | Sirolimus | 1.11 | uM | LJP6 | 1 | L15 | 72 | hr | 1657 | 3668 | 5505 | 0.6662 | 0.5224 |
| BT-20 | Sirolimus | 1.11 | uM | LJP6 | 2 | L15 | 72 | hr | 1657 | 3914 | 5505 | 0.7109 | 0.5864 |