LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 Mitoxantrone
3.33
uM
LJP5
 1
C20
 72
hr
 1657 1353 5505 0.2458 -0.0792
BT-20 Mitoxantrone
3.33
uM
LJP5
 2
C20
 72
hr
 1657 1180 5505 0.2143 -0.1242
BT-20 Mitoxantrone
3.33
uM
LJP5
 3
C20
 72
hr
 1657 1636 5505 0.2972 -0.0056
BT-20 Mitoxantrone
3.33
uM
LJP6
 1
C20
 72
hr
 1657 1093 5505 0.1985 -0.1468
BT-20 Mitoxantrone
3.33
uM
LJP6
 2
C20
 72
hr
 1657 1442 5505 0.2619 -0.0561
BT-20 Mitoxantrone
3.33
uM
LJP6
 3
C20
 72
hr
 1657 1331 5505 0.2418 -0.0849
BT-20 MK2206
3.33
uM
LJP6
 1
F02
 72
hr
 1657 2747 5505 0.4989 0.2831
BT-20 MK2206
3.33
uM
LJP6
 2
F02
 72
hr
 1657 2984 5505 0.5420 0.3447
BT-20 MK2206
3.33
uM
LJP6
 3
F02
 72
hr
 1657 3074 5505 0.5583 0.3681
BT-20 Neratinib
3.33
uM
LJP5
 1
A14
 72
hr
 1657 3369 5505 0.6119 0.4447
BT-20 Neratinib
3.33
uM
LJP5
 2
A14
 72
hr
 1657 3387 5505 0.6152 0.4494
BT-20 Neratinib
3.33
uM
LJP5
 3
A14
 72
hr
 1657 3190 5505 0.5794 0.3982
BT-20 Nilotinib
3.33
uM
LJP5
 1
N14
 72
hr
 1657 5530 5505 1.0044 1.0063
BT-20 Nilotinib
3.33
uM
LJP5
 2
N14
 72
hr
 1657 5961 5505 1.0827 1.1183
BT-20 Nilotinib
3.33
uM
LJP5
 3
N14
 72
hr
 1657 5239 5505 0.9516 0.9307
BT-20 Nintedanib
3.33
uM
LJP6
 1
H02
 72
hr
 1657 4306 5505 0.7821 0.6882
BT-20 Nintedanib
3.33
uM
LJP6
 2
H02
 72
hr
 1657 4357 5505 0.7914 0.7015
BT-20 Nintedanib
3.33
uM
LJP6
 3
H02
 72
hr
 1657 4633 5505 0.8415 0.7732
BT-20 NU7441
3.33
uM
LJP5
 1
C08
 72
hr
 1657 5736 5505 1.0418 1.0599
BT-20 NU7441
3.33
uM
LJP5
 2
C08
 72
hr
 1657 5236 5505 0.9510 0.9299
BT-20 NU7441
3.33
uM
LJP5
 3
C08
 72
hr
 1657 5127 5505 0.9312 0.9016
BT-20 Dactolisib
3.33
uM
LJP5
 1
M14
 72
hr
 1657 1784 5505 0.3240 0.0328
BT-20 Dactolisib
3.33
uM
LJP5
 2
M14
 72
hr
 1657 1815 5505 0.3297 0.0409
BT-20 Dactolisib
3.33
uM
LJP5
 3
M14
 72
hr
 1657 1821 5505 0.3308 0.0424
BT-20 NVP-TAE684
3.33
uM
LJP6
 1
K14
 72
hr
 1657 2707 5505 0.4917 0.2727